Due to the climate change and increased attention toward environmental management issues, the agri-food sector has been extensively relying on research, development, and innovation (RDi) to transform conventional agricultural production into a sustainable and eco-friendly industry. While the academic contribution of research has been relatively easily identified in the literature, the assessment of its societal impact remains underdeveloped. Accordingly, this study employs mixed-method evaluation approaches, mainly ASIRPA framework and Impact Oriented Monitoring (IOM) model to better understand and measure the multidimensional impacts of RDi in the agri-food sector in Spain. The objective of this analysis is to identify the impact of research on the society and the ecosystem. An in-depth case study analysis is conducted to examine the "best practices" program to promote sustainable techniques in the rice cultivation. Empirical findings suggest a standardized index to measure the economic, socio-territorial, health, political, capacity building, and environmental impacts, involving the stakeholder-network evaluation. The study highlights important implications for firm management decisions monitoring research uptake and policy design in the agri-food sector.