To address current challenges regarding sustainable development of wastewater treatment and provide scientific support in decision procedures towards sustainable solutions, new approaches, frameworks and methodologies about different possible solutions and their potential sustainability implications are needed. One way to facilitate sustainability assessment of wastewater is Life Cycle Assessment (LCA) methodology; however, it fails to map the full scope of wastewater impacts. This paper presents a framework to evaluate the performance of Wastewater Treatment Facilities (WWTF) taking into consideration various factors for insuring environmental sustainability. A total of nine indicators, seven environmental and two economic related to four wastewater treatment facilities, were assessed. Apart from evaluating the sustainability, this study also discussed the link of life cycle approach and social aspects of wastewater. The results show that for the environmental dimension using LCA provides information on different types of environmental activities and different impact categories. LCA can thus be used to quantify and compare the multiple types of impacts caused by one type of use or emission, as well as the various resource uses or emissions that contribute to one type of impacts. For the economic dimension, there is still a need for consistent and robust indicators and methods. The empirical results suggest that the environmental sustainability framework can be used in the first phase of the decision procedure that leads to a strategic choice for sustainable resource recovery from wastewater in developing countries. This motives researchers and decision-makers to consider the whole picture, and not just individual aspects, when considering different futures scenarios.