Virtual teamwork is a growing mode of operation within organizations through the increasing sophistication and accessibility of computer-mediated communication. The purpose of this paper was to develop a new conceptual framework and propositions to assist understanding of a new training phenomenon. The approach used was the integration of related, but distinct, literatures and development of arguments for the important role of cultural factors in virtual training teaming. We argue that delivery of training through teamwork in virtual spaces is potentially effective, and individualist and collectivist orientations of team members are likely to be critical for the effectiveness, or otherwise, of such programs.