A hairpin-contained i-motif guided DNA nanoantenna for sensitive and specific sensing of tumor extracellular pH gradients
Wenjie Ma,
Yuchen Wu,
Jinyan Li
et al.
Abstract:Inspired by the stimuli-responsive behavior of antennas receiving external signals, we designed a pH-stimulated and aptamer-anchored Y-shaped DNA nanoantenna for sensitive and specific sensing of tumor extracellular pH gradients.
Nanostructures integrating pH-sensitive DNA motifs have emerged as versatile platforms for active tumor targeting, owing to their capacity to undergo conformation changes in response to the common acidic environment of...
Nanostructures integrating pH-sensitive DNA motifs have emerged as versatile platforms for active tumor targeting, owing to their capacity to undergo conformation changes in response to the common acidic environment of...
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