A Health Economic Model to Determine the Cost-effectiveness of Cervical Cancer Screening Methods

Gemmen, Eric; Blackburne, Rose; Ulrich, A; Engen, Anke K. Van; Partlow, Kenny

doi:10.1097/00128360-200607000-00085

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“…In 1 preliminary cost-effectiveness model evaluation, the TIS was judged to be a highly cost-effective screening strategy. 28 The likelihood of cytology-negative patients with a single, positive, HC2 hrHPV DNA test of developing highly significant (CIN31) precancerous or malignant lesions in long-term (10-year) follow-up appears to be very low. In the Portland, Oregon, National Cancer Institute prospective risk study that used conventional Pap smears rather than LBC, the 10-year cumulative risk of developing CIN31 lesions was 3%-6% for conventional cytology-negative HC2 hrHPV DNA-positive women.…”

Section: Discussionmentioning

confidence: 99%

Very low human papillomavirus DNA prevalence in mature women with negative computer-imaged liquid-based Pap tests

Zhao

Elishaev

Yuan

et al. 2007

Cancer

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Background Endosonography has been successfully used in staging gastrointestinal cancer, but its value is as yet undetermined in laryngology. Methods This prospective study includes 84 patients undergoing microlaryngoscopy for laryngeal cancer. The results of endosonography were compared with those of CT and MRI in the 76 surgical cases. Results In the assessment of laryngal cancer, endosonography was superior to current imaging techniques, whereas CT and MRI showed similar results (accuracy of 89% vs 77% and 77%, respectively). Conclusions This study confirms that endosonography is highly effective in staging laryngeal cancer. Therefore, the latter may constitute a complementary diagnostic tool in these tumors and additionally may assist in choosing an adequate treatment. © 2012 Wiley Periodicals, Inc. Head Neck, 2013

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Section: Discussionmentioning

confidence: 99%