<div>Deep Reinforcement Learning (DRL) and Evolution Strategies (ESs) have surpassed human-level control in many sequential decision-making problems, yet many open challenges still exist.</div><div>To get insights into the strengths and weaknesses of DRL versus ESs, an analysis of their respective capabilities and limitations is provided. </div><div>After presenting their fundamental concepts and algorithms, a comparison is provided on key aspects such as scalability, exploration, adaptation to dynamic environments, and multi-agent learning. </div><div>Then, the benefits of hybrid algorithms that combine concepts from DRL and ESs are highlighted. </div><div>Finally, to have an indication about how they compare in real-world applications, a survey of the literature for the set of applications they support is provided.</div>