A hidradenitis suppurativa nőgyógyászati vonatkozásai

Abstract

Hidradenitis suppurativa is a chronic inflammatory disease of the hair follicles, usually presenting after puberty on the apocrine gland-bearing areas of the body. It usually flares up periodically and can lead to a severe condition affecting the 20–40-year-old childbearing age group. HS occurs more commonly in women. The main clinical features consist of painful, cicatrizing nodules and abscesses which develop mostly in the axillary, inguinal, genital and perianal regions and also on the breasts. HS is often accompanied by severe pain and malodorous discharge, both of which cause significant psychological stress and social stigma. Our main aim with this review paper is to highlight the gynecological aspects of this disease, as many times – due to the typical localization of the disease – patients seek gynecological care first when they experience the first symptoms of this disease. The most important classification of HS is the Hurley scale, which is based on the severity of the clinical symptoms. In recent years, numerous clinical trials have been conducted to seek optimized care of HS patients. Several drugs are used for the treatment of HS, but in most cases, the treatment has to be switched many times. It is of great importance to carefully follow comorbidities and possible pregnancies as in these cases, careful selection of treatment is required. Thus, HS is not only a dermatological, but also a gynecological disease. With an appropriate treatment and follow-up, the disease can be effectively handled. Orv Hetil. 2019; 160(8): 291–299.

Five-Year Remission of Hidradenitis Suppurativa Following the Removal of a Levonorgestrel Intrauterine Device and Disease Overview for Obstetrics and Gynecology Providers

“…Hurley stages I, II, and III correspond to mild disease, moderate disease, and severe disease, respectively (Table 1). Due to the intertriginous nature of this disease, obstetricians and gynecologists can reasonably be the first providers that detect HS presentations [3]. The pathophysiology of HS is believed to be multifactorial, including genetic, mechanical, and dietary influences in conjunction with hormone imbalance [4].…”

“…The pathophysiology of HS is believed to be multifactorial, including genetic, mechanical, and dietary influences in conjunction with hormone imbalance [4]. The degree of hormonal influence on HS occurrence and progression has not been fully elucidated; however, HS occurs more frequently in female patients, especially of childbearing age, has a propensity to premenstrual flares, generally improves during pregnancy, and is often improved through antiandrogen therapy, suggesting a role of hormonal influence on the pathogenesis of HS [3,[5][6][7]. In addition, various forms of hormonal birth control have been shown to affect HS, both positively and negatively.…”

Hidradenitis Suppurativa: An Interdisciplinary Problem in Dermatology, Gynecology, and Surgery—Pathogenesis, Comorbidities, and Current Treatments

“…Due to being underdiagnosed and under-treated, Hidradenitis suppurativa (HS) requires an interdisciplinary management approach to achieve optimal outcomes, considering the associated comorbidities. Consequently, HS should be regarded not only as a dermatological disorder but also as a gynecological and surgical disease [ 5 , 9 ].…”