In response to the large monitoring errors and incomplete consideration of fault locations in the operation status of wind turbines, this paper combined vibration signals and used a model constructed using nonlinear state estimation technology (NSET) to monitor and optimize the operation status of wind turbines. Firstly, it collected relevant SCADA (supervisory control and data acquisition) and vibration sensor data of Unit 5 of Guangdong Yangjiang Shaba Offshore Wind Farm on site, and used wavelet transform to denoise the vibration signal. Then, full consideration can be given to the faulty parts such as wind blades and gearboxes, and a model constructed by NSET using Markov distance to construct a process memory matrix can be used to monitor the status of the wind turbine equipment. Finally, the multi-level fuzzy comprehensive evaluation method can be used to optimize the comprehensive evaluation of the operating status of wind turbines, reducing monitoring errors.