“…[27][28][29] Therefore, the accurately simultaneous detection of AA, DA and UA in biological fluids is helpful for clinical diagnosis. Among the sensing materials, carbon materials with low toxicity and excellent conductivity were commonly used as modifier to improve the electrochemical performance of the sensor, including carbon nanotubes, [30] functionalized porous carbon, [31,32] graphenes such as reduced graphene oxide [33] and N-doped graphenes, [34,35] which are beneficial to the simultaneous determination of AA, DA and UA. To enrich the active sites and the catalytic activity, the noble metal nanoparticles [36,37] and some transition metals were incorporated in the modified layer, such as FeÀ Mn compound, [38] CoFe alloy, [39] especially cobalt, which was commonly act as the catalytic center to facilitate electrochemical redox of AA, DA and UA for the improvement of sensitivity.…”