A High-Strength and Biodegradable Zn–Mg Alloy with Refined Ternary Eutectic Structure Processed by ECAP

Huang, He; Liu, Huan; Wang, Lisha; Li, Yuhua; Agbedor, Solomon-Oshioke; Bai, Jing; Xue, Feng; Jiang, Jinghua

doi:10.1007/s40195-020-01027-x

Cited by 47 publications

(12 citation statements)

References 46 publications

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“…The raw materials used were pure Zn (99.99%) and pure Mg (99.99%). The ECAP process, which was described in previous studies, was used with twelve passes at 250 ℃ [17,18]. The size of the ECAP specimen is 45 mm of length, 20 mm of width and 20 mm of height.…”

Section: Preparation Of Zn-mg Alloysmentioning

confidence: 99%

Developing a Zn alloy with high strength and uniform elongation as a biomedical device

Chen,

Xiao,

et al. 2023

Mater. Res. Express

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The equal channel angular pressing (ECAP) process was used to develop a Zn-1Mg alloy with a tensile strength of 440 MPa and uniform elongation of 11%. The uniform elongation of the ECAPed Zn-1Mg alloy is higher than that of other Zn alloys with strengths over 400 MPa. The microstructure of the ECAPed Zn-1Mg alloy evolved through dynamic recrystallization (DRX), resulting in a refined grain structure. Additionally, the lamellar eutectic structure was fragmented into sub-micrometer particles (∼0.9 μm). The high strength of the Zn-1Mg alloy is due to both grain boundary strengthening and second phase strengthening. The high uniform elongation is attributed to the presence of plate-shaped precipitates with a high density of 1014m−2. The in-vitro results indicate that ECAPed Zn-1Mg alloy has high cell viability (>100%). Meanwhile, the Zn-1Mg alloy processed by ECAP exhibited better ALP activity and alizarin red results than pure Zn. These results demonstrate that Zn-1Mg alloy is beneficial to the proliferation and differentiation of osteoblasts, and also promote blood vascular formation. The good osteogenic and angiogenic properties of the alloy are attributed to the release of Mg2+ and Zn2+ during the degradation process, which play a critical role in biochemical reactions in the human body. Therefore, the high uniform elongation and good biological properties make Zn-Mg based alloys a promising material for expanding applications in the orthopedic field.

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Section: Preparation Of Zn-mg Alloysmentioning

confidence: 99%

Developing a Zn alloy with high strength and uniform elongation as a biomedical device

Chen,

Xiao,

et al. 2023

Mater. Res. Express

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“…Therefore, few comparative studies on these deformation methods have been performed to find the optimized method. Huang et al [ 82 ] studied the influence of extrusion, rolling, and ECAP on the microstructural and mechanical performance of Zn–Mg alloys. The maximum improvement in ductility and strength was achieved using ECAP.…”

Section: Zn-based Biomaterialsmentioning

confidence: 99%

Recent Developments in Zn-Based Biodegradable Materials for Biomedical Applications

Hussain

Ullah

Raza

et al. 2022

JFB

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Zn-based biodegradable alloys or composites have the potential to be developed to next-generation orthopedic implants as alternatives to conventional implants to avoid revision surgeries and to reduce biocompatibility issues. This review summarizes the current research status on Zn-based biodegradable materials. The biological function of Zn, design criteria for orthopedic implants, and corrosion behavior of biodegradable materials are briefly discussed. The performance of many novel zinc-based biodegradable materials is evaluated in terms of biodegradation, biocompatibility, and mechanical properties. Zn-based materials perform a significant role in bone metabolism and the growth of new cells and show medium degradation without the release of excessive hydrogen. The addition of alloying elements such as Mg, Zr, Mn, Ca, and Li into pure Zn enhances the mechanical properties of Zn alloys. Grain refinement by the application of post-processing techniques is effective for the development of many suitable Zn-based biodegradable materials.

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“…Lin et al 33 added Cu to Zn and found that the mechanical properties and degradation rates of the as-cast, hot-rolled and hot-rolled+cold-rolled Zn-3Cu alloy samples increased successively. Huang et al 30 proved that equal channel angular pressing can effectively improve the mechanical properties of as-cast Zn-1.6 Mg alloy, which are further improved with the increasing passes. However, some cardiovascular, biliary, and gastrointestinal implants have relatively small sizes and large specific surface areas, which doubtlessly affect the mechanical properties and degradation behavior of Zn alloys.…”

Section: Introductionmentioning

confidence: 99%

“…In addition to alloying, plastic deformation can also modify the mechanical properties and degradation behaviour of Zn alloys. To date, there are some studies of Zn-Cu, 23,[25][26][27] Zn-Mg, 21,[28][29][30] or Zn-Cu-Mg [31][32] alloys, with as-cast blocks, extruded bars, or as-rolled plates as the research objects. Lin et al 33 added Cu to Zn and found that the mechanical properties and degradation rates of the ascast, hot-rolled and hot-rolled+cold-rolled Zn-3Cu alloy samples increased successively.…”

Section: Introductionmentioning

confidence: 99%

Effect of Cu and Mg addition on the mechanical and degradation properties of Zn alloy wires

Cheng

Wang

et al. 2022

J Biomater Appl

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In this study, Zn-xCu (-0.1 Mg) wires with a diameter of 0.3 mm were obtained by hot extrusion and cold drawing. The microstructures, mechanical properties, and degradation behaviour were investigated to evaluate their feasibility as biodegradable metals. During the drawing process of the Zn-xCu alloys, many granular CuZn5 phases were dynamically precipitated, and the grains were significantly refined, along with a significant work softening with the tensile strength decreasing and the elongation increasing (from 161 MPa to 92 MPa and 22%–103% for Zn-0.2Cu). With the increase of Cu additions, the phenomenon of work softening was more intense and there was an opposite trend in the strength changes between the as-extruded rods (increase) and as-drawn wires (decrease). With 0.1 wt.% Mg added, the stable rod-like Mg2Zn11 phase was formed in as-extruded Zn-xCu-0.1 Mg rods, which obviously improved the strength, and inhibited the dynamic precipitation of granular CuZn5 phase and work softening phenomenon in the drawing process (from 332 MPa to 313 MPa and 11%–46% for Zn-0.2Cu-0.1 Mg). In addition, due to the micro-galvanic effect induced by the precipitates, alloying accelerated the degradation of Zn alloy wires, especially Zn-1Cu-0.1 Mg, which was related to the shape, distribution, and potential of the phases.

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A High-Strength and Biodegradable Zn–Mg Alloy with Refined Ternary Eutectic Structure Processed by ECAP

Cited by 47 publications

References 46 publications

Developing a Zn alloy with high strength and uniform elongation as a biomedical device

Developing a Zn alloy with high strength and uniform elongation as a biomedical device

Recent Developments in Zn-Based Biodegradable Materials for Biomedical Applications

Effect of Cu and Mg addition on the mechanical and degradation properties of Zn alloy wires

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