A highly potential acyclic Schiff base fluorescent turn on sensor for Zn2+ ions and colorimetric chemosensor for Zn2+, Cu2+ and Co2+ ions and its applicability in live cell imaging

Jayaraj, Anjitha; Gayathri, M.; Sivaraman, Gandhi; P, Chinna Ayya Swamy

doi:10.1016/j.jphotobiol.2021.112371

Cited by 39 publications

(15 citation statements)

References 52 publications

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“…Thermo Fisher Scientific NICOLET IS50 spectrophotometer was used to study Fourier Transform Infrared (FT-IR) spectra. The multinuclear 1 H and 13 C NMR spectra were recorded using BRUKER AVANCE II (400 MHz) and JEOL (AL 300 MHz) spectrophotometer in CDCl 3 , and chemical shifts (δ) were reported relative to tetramethylsilane. XEVO-G2-XS QTOF mass spectrometer was used to carry out mass spectral analysis.…”

Section: Methodsmentioning

confidence: 99%

“…[8][9][10][11] However, its deficiency can trigger severe health abnormalities such as aneurysms, pancytopenia, hernias, alterations in cholesterol metabolism, deterioration of the nervous system, and blood vessel disruption. [12,13] Copper can enter the human body through skin, from air while breathing, drinking water, or food. [14] Since the copper toxicity is increasing day by day, therefore, the determination of trace amounts in several matrices is fundamental to identify the copper contamination.…”

Section: Introductionmentioning

confidence: 99%

“…Si-CH 2 ) 13. C NMR (126 MHz, CDCl 3 ): δ 1.02, 3.21, 18.29, 24.03, 52.14, 58.54, 83.77, 120.61, 126.20, 128.47, 129.09, 130.14, 132.15, 134.44, 149.64, 153.45, 155.28, 160.87.…”

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confidence: 99%

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Intriguing interactions of triazolyl organosilane with copper (II) ion, blue copper protein, and silica nanoparticles: Spectral and theoretical approach

Singh

Kaur

Pawan

et al. 2022

Applied Organom Chemis

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In this manuscript, a concise library of 2‐Amino‐4‐chlorophenol‐based organosilanes 5(a‐c) was designed and synthesized by employing a multistep strategy and characterized with the help of NMR (1H and 13C) spectroscopic and mass spectrometry techniques. The silica nanoparticles loaded with 5a have been successfully synthesized and confirmed with the help of various techniques. Further, the interaction of probes 5a and its hybrid silica nanoparticles (A‐NPs) have been investigated towards various metal ions and exhibited favorable selectivity towards Cu2+ ions over other common metal ions in methanol with both colorimetric and fluorimetric read‐outs. The binding of probes 5a and A‐NPs with Cu2+ can be monitored by change of color in daylight and also by turn‐off fluorescence response in UV light. The sensing mechanism is ascribed to paramagnetic nature of Cu2+ ion leading to ligand to metal charge transfer and, hence, shows chelation enhanced fluorescence quenching (CHEQ) effect in the vicinity of ligands 5a and A‐NPs. The results demonstrated that the hybrid nanocomposites (A‐NPs) has even lower limit of detection and higher binding affinity as compared to probe 5a. The possible mechanism of 1:1 binding of 5a with Cu2+ could be substantiated by the density functional theory. Thus, this facile and appropriate sensing strategy may serve as a promising tool for selective and sensitive detection of Cu2+ ions. Moreover, the molecular docking studies provide valuable information regarding the interaction of compound 5a with the blue copper protein (plastocyanin). Hence, the current investigation provides a new avenue to design more potent organosilane analogs.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Intriguing interactions of triazolyl organosilane with copper (II) ion, blue copper protein, and silica nanoparticles: Spectral and theoretical approach

Singh

Kaur

Pawan

et al. 2022

Applied Organom Chemis

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“…Hence, it is of great significance to develop highly selective and sensitive fluorescent chemosensor to quantitatively detect Cu 2+ and Zn 2+ in biological and environmental fields. In this regard, fluorescent sensors for Cu 2+ and Zn 2+ detection have been designed based on various coordination scaffolds [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. For example, a naphthalene Schiff-base has been designed as a fluorescent sensor for Cu 2+ and Zn 2+ , where the fluorecence of sensor was quenched by Cu 2+ or enhanced by Zn 2+ over other metal cations in DMSO, respectively [11].…”

Section: Introductionmentioning

confidence: 99%

“…In this regard, a number of fluorescent sensors for Cu 2+ and Zn 2+ detection have been designed based on various coordination scaffolds. [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] For example, a naphthalene Schiff-base system was designed as a fluorescent sensor for Cu 2+ and Zn 2+ , where the fluorescence of the sensor was quenched by Cu 2+ or enhanced by Zn 2+ over other metal cations in DMSO, respectively. 11 Kim et al reported a phenanthrene-based multifunctional chemosensor that showed a slightly enhanced and blue-shifted (45 nm) fluorescence emission in the presence of Zn 2+ , whereas Cu 2+ caused a serious quenching of the original fluorescence.…”

Section: Introductionmentioning

confidence: 99%

A benzimidazole-derived fluorescent chemosensor for Cu(ii)-selective turn-off and Zn(ii)-selective ratiometric turn-on detection in aqueous solutions

Zhu

Zhang

2023

Sens. Diagn.

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Emission‐based sensing of cobalt (II) and vitamin B12 via a bis‐indole derivative

Mumcu,

Oncuoglu,

Hizliates

et al. 2024

Luminescence

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In this study, a bis‐indole compound was synthesized, characterized by 1H NMR, Fourier transform infrared, and mass spectroscopic measurements and used as a selective and efficient probe for the spectrofluorimetric analysis of Co (II). The cobalt‐induced quenching in the emission maximum at 567 nm was considered as the analytical signal in calibration studies. When encapsulated in a polymethyl methacrylate (PMMA) matrix, the bis‐indole compound exhibited a limit of detection (LOD) of 3.60 × 10–11 M for Co (II). Vitamin B12, which contains a cobalt ion in the center of a corrin ring in its structure, was also successfully quantified using the same probe. The bis‐indole compound showed a linear response based on quenching for increasing concentrations of vitamin B12, partially mimicking the contracted tetrapyrrole ring found naturally in the center of vitamin B12. The LOD for vitamin B12 was found to be 76 nm. Promising photophysical properties of the proposed probe, including high molar extinction coefficient, considerable quantum yield (0.46 and 0.64 in tetrahydrofuran and PMMA, respectively), high Stoke's shift and satisfactory photostability, make it a good choice for fluorescence‐based Co (II) determination. The ML3‐type stoichiometry of the complex between the dye and cobalt was elucidated both by Job's method and by high‐resolution mass spectrometry (HR‐MS).

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A highly potential acyclic Schiff base fluorescent turn on sensor for Zn2+ ions and colorimetric chemosensor for Zn2+, Cu2+ and Co2+ ions and its applicability in live cell imaging

Cited by 39 publications

References 52 publications

Intriguing interactions of triazolyl organosilane with copper (II) ion, blue copper protein, and silica nanoparticles: Spectral and theoretical approach

Intriguing interactions of triazolyl organosilane with copper (II) ion, blue copper protein, and silica nanoparticles: Spectral and theoretical approach

A benzimidazole-derived fluorescent chemosensor for Cu(ii)-selective turn-off and Zn(ii)-selective ratiometric turn-on detection in aqueous solutions

Emission‐based sensing of cobalt (II) and vitamin B12 via a bis‐indole derivative

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