A highly selective pyridoxal-based chemosensor for the detection of Zn(ii) and application in live-cell imaging; X-ray crystallography of pyridoxal-TRIS Schiff-base Zn(ii) and Cu(ii) complexes

Abstract

The synthesis, characterization, X-ray crystallography, and live-cell imaging of pyridoxal-TRIS Schiff-base ligand which is selective as a luminescence sensor to detect Zn(ii) ion, and the corresponding Zn(ii) and Cu(ii) complexes are described.

Small‐Molecule Fluorescent Probe: Ratiometric and Selective Detection of Sodium Ions for Imaging and Solid‐State Sensing Applications

“…Pyridoxal based probes were successfully applied to various analytes. [47][48][49][50][51][52][53][54][55][56] We have recently reported the selective turn-on fluorescence sensing of Zn(II) by pyridoxal based probe. [57] Synthesis of the novel pyridoxal based sodium(I) complex (NaL) with water coordination was performed by treating the L with sodium acetate (Scheme 2).…”

“…Pyridoxal based probes were successfully applied to various analytes [47–56] . We have recently reported the selective turn‐on fluorescence sensing of Zn(II) by pyridoxal based probe [57] .…”

Tri-armed Schiff base fluorescent sensor for the rapid recognition of Zn(ii): application in live cell imaging, test strips and TLC

“…However, the process of chelating Zn(II) is not completely understood when compared to different cations. 6 Moreover, zinc is associated with various physiological, structural and catalytic roles due to its redox state, Lewis-acid properties, kinetic liability and exibility of its coordination sphere. 7 There is a very minimal amount of zinc that must be consumed every day in order to maintain a scientic equilibrium.…”

New Schiff base salts as sources of blue and green light in the solid state: the role of the anion and protonation

“…Due to their fluorescent characteristics, Schiff bases find numerous applications, for instance in cellular bioimaging 24–27 and as organic light-emitting diodes (OLED), 28–32 selective sensors with high sensitivity for the determination of various cations, e.g. , Al 3+ , 33–35 Fe 3+ , 36–38 Ni 2+ (ref.…”

“…They may affect the spatial separation between the aromatic rings of the cationic Schiff base, possibly create additional molecular interactions, and influence the electron density of the fluorophore. [18][19][20][21][22][23] Due to their fluorescent characteristics, Schiff bases find numerous applications, for instance in cellular bioimaging [24][25][26][27] and as organic light-emitting diodes (OLED), [28][29][30][31][32] selective sensors with high sensitivity for the determination of various cations, e.g., Al 3+ , [33][34][35] Fe 3+ , [36][37][38] Ni 2+ (ref. [39][40][41][42] and pH indicators.…”