“…Zinc and copper are known to be the second and third most abundant transition metal elements in organisms, which are indispensable to many life processes. 1,2 Within the right concentration range in the human body, zinc ions (Zn 2+ ) play a crucial role in enzyme regulation, cellular transport and apoptosis, gene expression, as well as neural signal transmission. [3][4][5][6] When the homeostasis of Zn 2+ is disturbed, many diseases could occur, such as Alzheimer's disease, diabetes, immune dysfunction, ischemic stroke, and infantile diarrhea.…”