A Histomorphological Study of Nephrectomy Specimens in Rural Rajasthan- A Population Based Study

Gupta, Suraj; Sankhala, Kalpana; Sanwalka, Madhvi; Khatri, Jyotsana; Kumar, Deepak

doi:10.14260/jemds/2020/475

Cited by 2 publications

(6 citation statements)

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“…1 In present study, neoplastic lesions constituted 17(24.29%) cases which is similar to Suryawanshi et al and Kumar et al in which 9(27.27%) and 14(28%) cases of neoplastic lesions were present. 8,13 Among the neoplastic lesions, 13(76.47%) cases were malignant which is in concordance with the study done by Suryawanshi et al, Amin et al, Bajaj et al, Vinay et al and Kumar et al 8,9,[11][12][13] In our study maximum number of neoplastic as well as malignant cases were seen in males which is similar to Gupta et al, Suryawanshi et al and Amin et al 3,8,9 In the present study, clear cell renal cell carcinoma was the most common malignant neoplasm in adult and Wilms' tumour in children. All the cases of renal cell carcinoma were clinically diagnosed as malignant renal mass.…”

Section: Discussionsupporting

confidence: 91%

“…Severe cases of chronic renal disease like chronic infection, trauma, obstruction and malformation as well as renal malignancy destroy the renal parenchyma of both the kidneys resulting in chronic renal failure. 3 The treatment of choice for patient in end stage renal disease and neoplastic lesion is nephrectomy. The indication and type of nephrectomy depends on various factors like type of lesion: extent of damage, general condition of the patient and status of the contralateral kidney.…”

Section: Discussionmentioning

confidence: 99%

“…However, one of nephrectomy done for cyst removal was clinically not suspected to be neoplastic lesion, which histologically turned out to be clear cell renal cell carcinoma. 3,8,9,[14][15][16] Wilms' tumour formed the most common malignant pediatric tumor in studies by Amin et al, Bajaj et al, Shah et al and Aiman et al 9,11,14,15 Other malignant neoplasm included 1(7.69%) case each of papillary renal cell carcinoma type 2, chromophobe renal cell carcinoma, squamous cell carcinoma and metastatic small cell neuroendocrine tumor. Maximum number of renal cell carcinoma was in the age group of 41-50 years which is similar to the findings of Bajaj et al and Meena et al 11,16 In the study conducted by Gupta et al , Amin et al and Aiman et al 51 -70 years, 8 th decade and 61-70 years was the age group to which highest percentage of renal cell carcinoma fell in.…”

Section: Discussionmentioning

confidence: 99%

“…Maximum number of renal cell carcinoma was in the age group of 41-50 years which is similar to the findings of Bajaj et al and Meena et al 11,16 In the study conducted by Gupta et al , Amin et al and Aiman et al 51 -70 years, 8 th decade and 61-70 years was the age group to which highest percentage of renal cell carcinoma fell in. 3,9,15 The difference in the variation in age group is likely due to the small number of malignant cases under study. Among the 7 cases of clear cell renal cell carcinoma, maximum diameter of primary tumor was 9cm and least was 1.5cm.…”

Section: Discussionmentioning

confidence: 99%

“…2 Nephrectomy is one of the modalities of treatment that provides relief to patients from various chronic and life threatening diseases and in some cases makes way for renal transplant. 3 There are three types of nephrectomy which are performed for different indications which includes simple, partial and radical. Simple nephrectomy is indicated in patients with an irreversibly damaged kidney due to symptomatic chronic infection, obstruction, calculus disease or severe traumatic injury.…”

Section: Introductionmentioning

confidence: 99%

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Histomorphological Spectrum of Lesions in Nephrectomy Specimen

Basnet

Makaju

Dhakal

et al. 2021

J Coll Med Sci-Nepal

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Background Nephrectomy is a common and standard surgical practice in urology. It has pivotal role in diagnosis, treatment and prognosis of disease. It is indicated in patients with irreversible kidney damage following chronic infection, trauma, obstruction and malformation as well as renal malignancy. The objective of this study was to analyze the histomorphological spectrum of various lesions in nephrectomy specimens with special emphasis on grading and staging of renal carcinoma. Methods This is a retrospective study done from January 2015 to December 2020 in the Department of Pathology, Dhulikhel Hospital - Kathmandu University Hospital (DH - KUH). Relevant clinical data of the patients were obtained from the histopathological records of the patient from the pathology department. Results A total of 70 cases were studied, out of which 60 were simple nephrectomy specimens, followed by 8 radical and 2 partial nephrectomy specimens. The age of patient ranged from 2 to 74 years. Highest percentage of nephrectomy was seen in 4th decade of life. Male population comprising 54.28% of nephrectomy. Non-neoplastic lesions constituted 53 cases and chronic pyelonephritis was the most common lesion. Out of 17 neoplastic lesions, 76.47% of cases were malignant. Clear cell renal cell carcinoma was the most common malignant tumour. Conclusions This study gives a fair insight into the incidence of neoplastic and non-neoplastic lesions of kidney requiring nephrectomy in this institution.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Histomorphological Spectrum of Lesions in Nephrectomy Specimen

Basnet

Makaju

Dhakal

et al. 2021

J Coll Med Sci-Nepal

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Histomorphological Analysis of Nephrectomy Specimens

Kulkarni

Bm²,

Devi³

et al. 2022

Acta Medica International

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Introduction: For a range of kidney abnormalities, including both neoplastic and nonneoplastic disorders, nephrectomy is a popular surgical treatment. We conducted this study to examine the range of lesions found in the nephrectomy specimens obtained and to ascertain the distribution of these lesions by age and sex. Materials and Methods: This study was conducted in the department of pathology, from 2017 to 2022. All nephrectomy specimens received during 5 years were included. Results: The spectrum of renal lesions observed in the study included both neoplastic (43.75%) and nonneoplastic (56.25%) conditions. Nineteen patients were males (59.37%) and 13 were females (40.62%) (M: F = 1.4:1). The most common entity in the nonneoplastic category was chronic pyelonephritis (n = 9, 28.12%). In our study, we documented two unusual cases of renal replacement lipomatosis (RRL), a type of pseudotumor related to nonfunctioning kidneys. Fourteen patients underwent nephrectomy for neoplastic conditions such as Wilm's tumor and renal cell carcinoma (RCC). Conclusion: Nephrectomy for the nonneoplastic condition was performed more frequently in our series. Histopathological evaluation of nonneoplastic nephrectomy specimens must be thoroughly considered, particularly in unusual circumstances such as RRL, where a preoperative erroneous initial impression of a malignant lesion such as angiomyolipoma or liposarcoma is possible.

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A Histomorphological Study of Nephrectomy Specimens in Rural Rajasthan- A Population Based Study

Cited by 2 publications

References 32 publications

Histomorphological Spectrum of Lesions in Nephrectomy Specimen

Histomorphological Spectrum of Lesions in Nephrectomy Specimen

Histomorphological Analysis of Nephrectomy Specimens

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