A meta-analysis of randomized, controlled trials of social skills training for schizophrenia was conducted. Outcome measures from 22 studies including 1,521 clients were categorized according to a proximaldistal continuum in relation to the presumed site of action of skills training interventions, with content mastery tests and performance-based measures of skills assumed to be most proximal, community functioning and negative symptoms intermediate, and general symptoms and relapse most distal. Results reveal a large weighted mean effect size for content-mastery exams (d ϭ 1.20), a moderate mean effect size for performance-based measures of social and daily living skills (d ϭ 0.52), moderate mean effect sizes for community functioning (d ϭ 0.52) and negative symptoms (d ϭ 0.40), and small mean effect sizes for other symptoms (d ϭ 0.15) and relapse (d ϭ 0.23). These results support the efficacy of social skills training for improving psychosocial functioning in schizophrenia.Keywords: schizophrenia, social skills, meta-analysis Poor psychosocial functioning is one of the defining characteristics of schizophrenia (American Psychiatric Association, 1994). A wealth of evidence shows that impaired social skills in occupational, social, and recreational situations are strongly related to worse psychosocial adjustment in clients with schizophrenia Mueser & Bellack, 1998). Furthermore, impairments in social skill often predate the onset of schizophrenia (Hans, Auerbach, Asarnow, Styr, & Marcus, 2000), are present at the first episode (Addington, Saeddi, & Addington, 2006), are stable over time in the absence of psychosocial treatment (Mueser, Bellack, Douglas, & Morrison, 1991), and persist into senescence (Patterson, Goldman, McKibben, Davidson, & Jeste, 2001).Over the past 35 years, a variety of social skills training (SST) approaches have been developed to address impairments in social skills. Although skills training programs vary widely in content, duration, and the setting where they are implemented, they share a common set of strategies for teaching new skills based on social learning theory (Bandura, 1969), including goal setting, role modeling, behavioral rehearsal, positive reinforcement, corrective feedback, and homework assignments to help promote generalization to the community. Several narrative reviews of research on SST for schizophrenia have been recently published (e.g., Bellack, 2004;Kopelowicz, Liberman, & Zarate, 2006) but they have not included quantitative meta-analyses of the literature permitting direct comparisons of results across studies.Two comprehensive meta-analyses of the SST literature in schizophrenia (Benton & Schroeder, 1990) and severe mental illness (Dilk & Bond, 1996) were published over 10 years ago. Results of Benton and Schroeder's (1990) meta-analysis were relatively optimistic, with the authors concluding that effects of SST were large for specific behavioral measures of social skill and for self-reported social anxiety and assertiveness but smaller for measures of community f...