A hospital base epidemiology and pattern of acute adult poisoning across Iran: a systematic review

Moradi, Mahsa; Ghaemi, Kazem; Mehrpour, Omid

doi:10.19082/2860

Cited by 25 publications

(18 citation statements)

References 27 publications

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“…Consistent with other reports, pharmaceutical medications (44.14%) were regularly utilized agents for poisoning [18]. The predominance of poisoning with medicinal products might be related to the easy accessibility of different categories of medicines over-the-counter which might have led to the greatest proportion of poisoning by analgesics, antipyretics, sedatives, and antihypertensive in our study.…”

Section: Discussionsupporting

confidence: 91%

Patterns of Acute Poisoning Among Patients Treated in the Emergency Wards of a Tertiary Care Hospital: A Cross-Sectional Study

Revathi

Reddy

Prasanna

et al. 2018

Asian J Pharm Clin Res

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Objective: Poisoning is a growing health-care burden in developing countries like India. Predicting the nature of the intention behind poisoning and type of poisoning agent involved will help in facilitating appropriate treatment measures, hence, improving the patient’s quality of life.Methods: The prospective, observational study was conducted in a tertiary care multispecialty hospital for 6 months from November 2016 to April 2017 and involved a total of 133 patients. Treatment and outcomes of the patients were collected, documented in a data collection form. Chi-square test and logistic regression analysis were applied.Results: The mean age of the study participants was 27.76±15.5 with predominance seen in age groups of <30 years (59.3%), females (52.6%), and married (49.6%). Intentional poisoning (69.1%) through oral ingestion (81.2%) of medications (51.6%) in solid forms (60.2%) was predominant. Patients presenting with systemic manifestations (70.4%) arrived in a time duration >1 h (66.2%), received first aid (62.4%), and supportive care (52.7%). Higher ingestion of physical forms was significantly observed in both single (OR: 4.5) and married (OR: 3). The outcomes were correlated with poison severity score and patients with mild symptoms recovered (60.9%).Conclusion: The use of medicines for intentional poisoning continues to be rampant in younger age groups and married individuals. Educational programs with more accentuation on the data regarding toxic substances along with preventive measures are to be implemented to make mindfulness among the overall population.

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Section: Discussionsupporting

confidence: 91%

Patterns of Acute Poisoning Among Patients Treated in the Emergency Wards of a Tertiary Care Hospital: A Cross-Sectional Study

Revathi

Reddy

Prasanna

et al. 2018

Asian J Pharm Clin Res

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“…Poisoning is one of the major concerns of the health system in every country. In Iran, poisoning is one of the leading causes of hospitalization and death (1), and about 20% of hospital admissions are due to poisoning (2). Carbon monoxide (CO) poisoning, as one of the lethal poisoning, is responsible for a large percentage of poisonings and accidental deaths (3).…”

Section: Introductionmentioning

confidence: 99%

Deaths from Carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

Alimohamadi¹,

Rahimi²,

Mehri³

2020

Preprint

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Background: Carbon monoxide (CO) poisoning, as one of the lethal poisoning, is responsible for a large percentage of poisonings and accidental deaths. Since the investigation of the mortality and the distribution of CO poisoning deaths in Iranian provinces is still unknown and no study has investigated so far, this study was conducted to determine the trend of mortality rate changes due to CO poisoning by Spatio-temporal analysis in Iran from 2011 to 2018. Methods: An ecological study was conducted based on data from the reports of at the National Center for Statistics of Iran for eight years from 21 March 2011 to 21 March 2018. The number of deaths due to CO poisoning and the annual mortality rates of CO poisoning per 100,000 population were calculated. The Spatio-temporal analysis used to determine the spatial and temporal distribution of deaths.Results: A total of 6078 deaths were reported due to CO poisoning that 4497 death were male (74%) and 1596 were female (26%) from 2011 to 2018. In both sexes, the mortality rate due to CO poisoning was 1.26 from 2011 to 0.91 in 2018. According to the results, the overall male-to-female ratio was 2.8. The mortality rate due to CO Poisoning had a decreasing trend. However, this trend did not have a linear trend (p=0.37). Our results showed that most of the deaths due to CO poisoning are higher in the northern and western provinces of Iran.Conclusion: This study is one of the first studies to compare the spatial and temporal mortality rates due to CO poisoning in Iran. Paying attention to general education about the principles of safety in the installation of heaters and the use of the gas networks, continuous and accurate monitoring of the installation and operation of CO-producing, and the use of sensitive alarms can reduce mortality and morbidity due to CO poisoning.

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“…A poison is a xenobiotic that, in the right dose, can lead to injury or death of an organism [ 1 ]. Poisoning is a common, resource intensive chief complaint resulting in thousands of hospital admissions worldwide.…”

Section: Introductionmentioning

confidence: 99%

Epidemiological and clinical profiles of acute poisoning in patients admitted to the intensive care unit in eastern Iran (2010 to 2017)

et al. 2018

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BackgroundAcute poisoning is a common chief complaint leading to emergency department visits and hospital admissions in developing countries such as Iran. Data describing the epidemiology of different poisonings, characteristics of the clinical presentations, and the predictors of outcome are lacking. Such data can help develop more efficient preventative and management strategies to decrease morbidity and mortality related to these poisonings. This manuscript describes the epidemiology of acute poisoning among patients admitted to the intensive care unit (ICU) in Birjand, Iran.MethodsThis retrospective, cross-sectional study was conducted to characterize acute poisonings managed in the ICU during a 7-year period from March 2010 to March 2017 in a single center in Birjand, Iran. Patient characteristics, suspected exposure, the route of exposure, and outcome data were collected from hospital medical records.ResultsDuring the study period, 267 (64% male and 36% female) patients met inclusion criteria. Pharmaceutical medication (36.6%), opioids (26.2%) followed by pesticides (13.9%) were the most common exposures 38.2% of these cases were identified as suicide attempts. There were different frequencies in terms of xenobiotic exposure in relation to gender (p = 0.04) and the survival (p = 0.001). There was a significant difference between various xenobiotics identified as the cause of poisoning (p = 0.001). Mortality rate in our study was 19.5%. The incidence of outcomes was significantly higher in patients poisoned with opioids, pesticides, benzodiazepines, and tricyclic antidepressants (p < 0.05). The median length of hospital stay was higher in pesticide-poisoned patients (p = 0.04).ConclusionOpioids and pesticides were the most common exposures. The mortality rate of the poisoned patients in the ICU was proportionately high. The mortality rate due to opioid poisoning is a major concern and the most significant cause death due to poisoning in the region. Further monitoring and characterization of acute poisoning in Birjand, Iran is needed. These data can help develop educational and preventative programs to reduce these exposures and improve management of exposures in the prehospital and hospital settings.

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A hospital base epidemiology and pattern of acute adult poisoning across Iran: a systematic review

Cited by 25 publications

References 27 publications

Patterns of Acute Poisoning Among Patients Treated in the Emergency Wards of a Tertiary Care Hospital: A Cross-Sectional Study

Patterns of Acute Poisoning Among Patients Treated in the Emergency Wards of a Tertiary Care Hospital: A Cross-Sectional Study

Deaths from Carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study

Epidemiological and clinical profiles of acute poisoning in patients admitted to the intensive care unit in eastern Iran (2010 to 2017)

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