A Huge Pleomorphic Liposarcoma of the Retroperitoneum

Abstract

oft tissue sarcomas (STS) are rare and locally invasive tumors.The most common type of soft tissue sarcomas is liposarcomas. It consists of <1% of all malignant tumors in adulthood.1,2 Retroperitoneal liposarcoma (RLS), is a rare, biologically heterogeneous tumor that presents considerable challenges due to its size and deep location.1 85% of RLS are malignant tumors that remain occult for long periods and grow quite large. Their typical symptoms are discomfort, pain or a palpable mass due to large size. These tumors occur most frequently in men, generally in the fifth or sixth decade of life. Magnetic resonance imaging (MRI) provide reliable data about localization of mass and relationship between vascular structures. Although complete surgical resection is mandatory for extending survival, the majority of patients with huge RLS will develop locally recurrent disease following surgery. [1][2][3] So that patients should be followed routinely in every 3 months during first two years . 4 Pleomorphic liposarcoma is the rarest subtype and is a high grade tumor. The risk of recurrence and metastatis with liposarcoma increases with higher grade. Herein, we report a case of a 68 year-old man with a 35 cm mass adjacent to kidney with synchronous inguinal 7 cm mass. CASE REPORTA 68 year-old man, who had been suffering from progressive enlargement and discomfort of abdomen with weight loss during last 3 months.Other past medical and familly histories were unremarkable. On physical examination, a palpable mass on the right flank was found. The abdomen was extremely swollen, tense and dilated veins were apparent over abdomen. A AB BS S T TR RA AC CT T Retroperitoneal liporsarcoma (RLS) is a rare, highly malignant tumor with poor prognosis and high recurrence rate. Pleomorphic liposarcoma is the rarest subtype and is a high grade tumor with cells with very different appearance from normal cells.Herein we report a case of a 68 year-old man with a 35 cm mass adjacent to kidney with synchronous inguinal 7 cm mass. The patient was operated in our clinic and pathology revealed plemorphic liposarcoma. The case was discussed because of its rarity and two mass in the two distinct region.K Ke ey yw wo or rd ds s: : Retroperitoneal liposarcoma; liposarcoma; nephrectomy