A Huge Polypoid Type Early Gastric Neuroendocrine Cell Carcinoma

Abstract

We report a case of a huge polypoid-type early gastric neuroendocrine cell carcinoma. Upper gastrointestinal endoscopy in a 77-year-old man revealed a gastric polyp on the anterior wall of the corpus. Endoscopically biopsied material from the polyp suggested that the lesion was malignant; specifically a poorly and moderately differentiated tubular adenocarcinoma or adenocarcihoma with neuroendocrine differentiation. Endoscopically the lesion was a huge polypoid type with a broad stalk approximately 40 mm in diameter, and its surface was lobulated with a white coat and erosion. The patient underwent total gastrectomy. The resected specimen histopathologically showed a polypoid mass with medullary carcinoma and indicated endocrine cell differentiation. Immunohistochemical findings supported the diagnosis of endocrine cell carcinoma. This case was an early and polypoid-type gastric endocrine cell carcinoma. Since examples of such cases are rare in the literature, we report this case in brief. (Dig Endosc 1998 ; 10 : 236-239)

Unusual endoscopic findings of gastric neuroendocrine tumor

“…One case showed the morphology of submucosal tumor. A rare polypoid type early NEC in the stomach was reported (16). Endoscopic findings of the tumor also demonstrated a polypoid lesion with a broad stalk.…”