A Hybrid Bioimpedance Spectroscopy Architecture for a Wide Frequency Exploration of Tissue Electrical Properties

Lamlih, Achraf; Freitas, Philippe; Belhaj, Mohamed-Moez; Salles, Jérémie; Kerzérho, Vincent; Soulier, Fabien; Bernard, Serge; Rouyer, Tristan; Bonhommeau, Sylvain

doi:10.1109/vlsi-soc.2018.8644829

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…The electrical characteristics of organisms will change with different organs and tissues. Generally, the impedance characteristics of different tissues are quite different (Lamlih et al, 2018). Table 1 is electrical conductivity of some common tissues and organs.…”

Section: Electrical Impedance Characteristics Of Biological Tissues Biological Electrical Characteristics Of Electric Currentmentioning

confidence: 99%

The Research Progress of Electrical Impedance Tomography for Lung Monitoring

Shi

Yang

Xie

et al. 2021

Front. Bioeng. Biotechnol.

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Medical imaging can intuitively show people the internal structure, morphological information, and organ functions of the organism, which is one of the most important inspection methods in clinical medical diagnosis. Currently used medical imaging methods can only be applied to some diagnostic occasions after qualitative lesions have been generated, and the general imaging technology is usually accompanied by radiation and other conditions. However, electrical impedance tomography has the advantages of being noninvasive and non-radiative. EIT (Electrical Impedance Tomography) is also widely used in the early diagnosis and treatment of some diseases because of these advantages. At present, EIT is relatively mature and more and more image reconstruction algorithms are used to improve imaging resolution. Hardware technology is also developing rapidly, and the accuracy of data collection and processing is continuously improving. In terms of clinical application, EIT has also been used for pathological treatment of lungs, the brain, and the bladder. In the future, EIT has a good application prospect in the medical field, which can meet the needs of real-time, long-term monitoring and early diagnosis. Aiming at the application of EIT in the treatment of lung pathology, this article reviews the research progress of EIT, image reconstruction algorithms, hardware system design, and clinical applications used in the treatment of lung diseases. Through the research and introduction of several core components of EIT technology, it clarifies the characteristics of EIT system complexity and its solutions, provides research ideas for subsequent research, and once again verifies the broad development prospects of EIT technology in the future.

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Section: Electrical Impedance Characteristics Of Biological Tissues Biological Electrical Characteristics Of Electric Currentmentioning

confidence: 99%

The Research Progress of Electrical Impedance Tomography for Lung Monitoring

Shi

Yang

Xie

et al. 2021

Front. Bioeng. Biotechnol.

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show abstract

“…; and γ, >10 MHz, for content measurement of the biological species (intracellular fluid level), etc. [24,29,30]. Since pain is an electrical signal transmitted by dynamics of potassium channels signaling among intra-and extracellular fluid, it seems natural to choose the lowest frequency dispersion for exciting the skin with our device.…”

Section: Multisine Designmentioning

confidence: 99%

Bioimpedance Sensor and Methodology for Acute Pain Monitoring

Ghita

Neckebroek

Juchem

et al. 2020

Sensors

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The paper aims to revive the interest in bioimpedance analysis for pain studies in communicating and non-communicating (anesthetized) individuals for monitoring purpose. The plea for exploitation of full potential offered by the complex (bio)impedance measurement is emphasized through theoretical and experimental analysis. A non-invasive, low-cost reliable sensor to measure skin impedance is designed with off-the-shelf components. This is a second generation prototype for pain detection, quantification, and modeling, with the objective to be used in fully anesthetized patients undergoing surgery. The 2D and 3D time–frequency, multi-frequency evaluation of impedance data is based on broadly available signal processing tools. Furthermore, fractional-order impedance models are implied to provide an indication of change in tissue dynamics correlated with absence/presence of nociceptor stimulation. The unique features of the proposed sensor enhancements are described and illustrated here based on mechanical and thermal tests and further reinforced with previous studies from our first generation prototype.

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“…In addition, it has already been shown that mathematical formulation is an important tool in characterization of drug tissue trapping [18]. The rationale of using bioimpedance spectroscopy is that it allows a rigorous characterization of the biological tissue electrical properties influenced by nociception [19,20]. The in-house developed prototype and methodology have the advantage to follow a customizable input signal that excites the tissue over a range of frequencies.…”

Section: Introductionmentioning

confidence: 99%

Pain Detection with Bioimpedance Methodology from 3-Dimensional Exploration of Nociception in a Postoperative Observational Trial

Neckebroek

Ghita

et al. 2020

JCM

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Although the measurement of dielectric properties of the skin is a long-known tool for assessing the changes caused by nociception, the frequency modulated response has not been considered yet. However, for a rigorous characterization of the biological tissue during noxious stimulation, the bioimpedance needs to be analyzed over time as well as over frequency. The 3-dimensional analysis of nociception, including bioimpedance, time, and frequency changes, is provided by ANSPEC-PRO device. The objective of this observational trial is the validation of the new pain monitor, named as ANSPEC-PRO. After ethics committee approval and informed consent, 26 patients were monitored during the postoperative recovery period: 13 patients with the in-house developed prototype ANSPEC-PRO and 13 with the commercial device MEDSTORM. At every 7 min, the pain intensity was measured using the index of Anspec-pro or Medstorm and the 0–10 numeric rating scale (NRS), pre-surgery for 14 min and post-anesthesia for 140 min. Non-significant differences were reported for specificity-sensitivity analysis between ANSPEC-PRO (AUC = 0.49) and MEDSTORM (AUC = 0.52) measured indexes. A statistically significant positive linear relationship was observed between Anspec-pro index and NRS (r2 = 0.15, p < 0.01). Hence, we have obtained a validation of the prototype Anspec-pro which performs equally well as the commercial device under similar conditions.

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A Hybrid Bioimpedance Spectroscopy Architecture for a Wide Frequency Exploration of Tissue Electrical Properties

Cited by 4 publications

References 8 publications

The Research Progress of Electrical Impedance Tomography for Lung Monitoring

The Research Progress of Electrical Impedance Tomography for Lung Monitoring

Bioimpedance Sensor and Methodology for Acute Pain Monitoring

Pain Detection with Bioimpedance Methodology from 3-Dimensional Exploration of Nociception in a Postoperative Observational Trial

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