The smart agriculture domain refers to the usage of technologies such as the Internet of Things (IoT), sensors, location systems, robots and Artificial Intelligence implemented on farms. The goal is to increase the quality and quantity of crop production while motivating viticulturists to implement new technologies as well as streamline production costs. The study's purpose is to monitor environmental conditions (soil temperature and humidity, air temperature and humidity) and to analyse diseased leaves from the vineyard using an intelligent, integrated decision support system for vineyard management that is based on the IoT end-to-end solution. This method suggests placing IoT sensors inside wine crops to measure environmental conditions, which are then sent and stored in the Cloud. Also, an Unmanned Aerial Vehicle (UAV) is used to capture images containing healthy and diseased leaves (powdery mildew, downy mildew, gray rot) from various regions of the vineyard. These images are analysed by implementing a Machine Learning algorithm that detects the state of the leaf. Following the analysis, the results are presented as graphs and charts, allowing the viticulturist to proceed with the necessary actions.