A hybridized nano-porous carbon reinforced 3D graphene-based epidermal patch for precise sweat glucose and lactate analysis

Asaduzzaman, Md; Zahed, Md Abu; Sharifuzzaman, Md.; Reza, Md Selim; Xue, Hui; Sharma, Sudeep; Shin, Young Do; Park, Jae Yeong

doi:10.1016/j.bios.2022.114846

Cited by 43 publications

(19 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The hydrophilic oxygen groups and multiple aromatic parts in GO could also assist in obtaining a stable GO-CNT complex with a strong 𝜋-𝜋 stacking interaction. Considering the catalytic activity of various metals and their alloys, [39][40][41][42][43][44] the LIG electrode modified by the carbonbased nanomaterials is further decorated with metal nanoparticles followed by laser treatment for enhanced electrochemical properties.…”

Section: Nanocomposite Modificationmentioning

confidence: 99%

A Highly Sensitive and Long‐Term Stable Wearable Patch for Continuous Analysis of Biomarkers in Sweat

Lorestani,

Zhang,

Abdullah

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

Although increasing efforts have been devoted to the development of non‐invasive wearable electrochemical sweat sensors for monitoring physiological and metabolic information, most of them still suffer from poor stability and specificity over time and fluctuating temperatures. This study reports the design and fabrication of a long‐term stable and highly sensitive flexible electrochemical sensor based on nanocomposite‐modified porous graphene by facile laser treatment for detecting biomarkers such as glucose in sweat. The laser‐reduced and patterned stable conductive nanocomposite on the porous graphene electrode provides the resulting glucose sensor with an excellent sensitivity of 1317.69 µA mm−1 cm−2 and an ultra‐low limit of detection of 0.079 µm. The sensor can also detect pH and exhibit extraordinary stability to maintain more than 91% sensitivity over 21 days in ambient conditions. Taken together with a temperature sensor based on the same material system, the dual glucose and pH sensor integrated with a flexible microfluidic sweat sampling network further results in accurate continuous on‐body glucose detection calibrated by the simultaneously measured pH and temperature. The low‐cost, highly sensitive, and long‐term stable platform could facilitate the early identification and continuous monitoring of different biomarkers for non‐invasive disease diagnosis and treatment evaluation.

show abstract

Section: Nanocomposite Modificationmentioning

confidence: 99%

A Highly Sensitive and Long‐Term Stable Wearable Patch for Continuous Analysis of Biomarkers in Sweat

Lorestani,

Zhang,

Abdullah

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

show abstract

“…The sheet resistance of 43.5 Ω sq −1 is a good resistance value for its wide applications in flexible electronics and eskin applications. [20,21,32] Similarly, the meso/microporous structure of H-NPC is responsible for increasing the surface area of bare LIG. [42] The increase in surface area of LIG electrodes was verified via the continuous absorption and desorption of N 2 using Braunauer-Emmett-Teller (BET) analysis (Figure 2h).…”

Section: Materials Characterizationmentioning

confidence: 99%

“…[ 20 ] This issue can be addressed by incorporating fillers into LIG such as metal‐organic framework (MOF). [ 21,22 ] MOFs are crystalline nanomaterials, where the inorganic metal ions and organic ligands are bound together by powerful coordination bonds. [ 23 ] The crystalline MOF structures offer a high interior surface area with high porosity and provide many active sites for the storage of charge.…”

Section: Introductionmentioning

confidence: 99%

A Breathable, Reliable, and Flexible Siloxene Incorporated Porous SEBS‐Based Triboelectric Nanogenerator for Human–Machine Interactions

Shrestha,

Pradhan,

Asaduzzaman

et al. 2023

Advanced Energy Materials

Self Cite

View full text Add to dashboard Cite

The breathability of wearable sensors is of utmost necessity as it facilitates heat dissipation and sweat evaporation from the skin–sensor interface for improving the user's comfort and minimizing the inflammation risk. In this work, a Siloxene/porous styrene–ethylene–butylene–styrene (SEBS)‐based breathable triboelectric sensor is newly designed and fabricated for increasing user comfort and reliability. The reliability of the fabricated sensor is evaluated by measuring the heat dissipation through the skin–sensor interface using a thermal IR imaging test. Similarly, the sensor's breathability is quantified through a water vapor transmission rate (WVTR) test, where the achieved breathability of 5.88 mg cm−2 h−1 is sufficient for sweat evaporation, as an average person loses 1.2–4.2 mg cm−2 h−1 of sweat. Furthermore, a porous, metal‐free, hybridized nanoporous carbon (H‐NPC)/laser‐induced graphene (LIG) is utilized as a charge‐collecting electrode, which is transferred and conformally attached to the Siloxene/SEBS substrate. This results in a reduction in the interfacial resistance and an improvement in bonding between the dielectric and electrode layers. With a pressure sensitivity of 0.75 VkPa−1, the fabricated sensor demonstrates successful application in gesture recognition. Thus, this research showcases the considerable potential for developing triboelectric naongenerators (TENGs) with breathable and reliable features and underscores their broad applicability in human–machine interfaces and soft robotics systems.

show abstract

“…However, the structural frangibility of LIG limits their application in wearable devices. 33 To address its structural instability, LIG is typically transferred to a poly(dimethylsiloxane) (PDMS) substrate due to its advantageous flexibility, hydrophobicity, and robustness. However, this process unfortunately leads to a decrease in both the surface area and the conductivity of the LIG.…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Siloxene-Decorated Laser-Inscribed Graphene Patch for Sweat Ion Analysis and Electrocardiogram Monitoring

Hui,

Asaduzzaman,

Zahed

et al. 2024

ACS Appl. Mater. Interfaces

Self Cite

View full text Add to dashboard Cite

Potentiometric detection in complex biological fluids enables continuous electrolyte monitoring for personal healthcare; however, the commercialization of ion-selective electrode-based devices has been limited by the rapid loss of potential stability caused by electrode surface inactivation and biofouling. Here, we describe a simple multifunctional hybrid patch incorporating an Au nanoparticle/siloxene-based solid contact (SC) supported by a substrate made of laser-inscribed graphene on poly(dimethylsiloxane) for the noninvasive detection of sweat Na + and K + . These SC nanocomposites prevent the formation of a water layer during ion-to-electron transfer, preserving 3 and 5 μV/h potential drift for the Na + and K + ion-selective electrodes, respectively, after 13 h of exposure. The lamellar structure of the siloxene sheets increases the SC area. In addition, the electroplated Au nanoparticles, which have a large surface area and excellent conductivity, further increased the electric double-layer capacitance at the interface between the ion-selective membranes and solid-state contacts, thus facilitating ion-to-electron transduction and ultimately improving the detection stability of Na + and K + . Furthermore, the integrated temperature and electrocardiogram sensors in the flexible patch assist in monitoring body temperature and electrocardiogram signals, respectively. Featuring both electrochemical ion-selective and physical sensors, this patch offers immense potential for the self-monitoring of health.

show abstract

A hybridized nano-porous carbon reinforced 3D graphene-based epidermal patch for precise sweat glucose and lactate analysis

Cited by 43 publications

References 43 publications

A Highly Sensitive and Long‐Term Stable Wearable Patch for Continuous Analysis of Biomarkers in Sweat

A Highly Sensitive and Long‐Term Stable Wearable Patch for Continuous Analysis of Biomarkers in Sweat

A Breathable, Reliable, and Flexible Siloxene Incorporated Porous SEBS‐Based Triboelectric Nanogenerator for Human–Machine Interactions

Multifunctional Siloxene-Decorated Laser-Inscribed Graphene Patch for Sweat Ion Analysis and Electrocardiogram Monitoring

Contact Info

Product

Resources

About