The experimental environment of the JUNO is a spherical container filled with a liquid scintillator (alkylbenzene) with a diameter of about 35 m. To observe neutrino interactions in alkylbenzene with photomultiplier tubes (PMTs) and to precisely measure the neutrino properties in this environment, it is necessary to design a high-precision localization system for the PMT device. In this paper, we report the design of an ultrasonic localization system with a symmetrical receiving array, based on the construction of an experimental setup that reproduces the configuration of JUNO’s environment. We show through positioning consistency and accuracy measurements that the ultrasonic localization system has a high localization accuracy and can perform effective localization in an alkylbenzene solution with 98% purity.