A Janus nanofibrous scaffold integrated with exercise-driven electrical stimulation and nanotopological effect enabling the promotion of tendon-to-bone healing

Zhang, Qian; Zhu, Jianhua; Fei, Xiang; Zhu, Meifang

doi:10.1016/j.nantod.2024.102208

Nano Today

2024

DOI: 10.1016/j.nantod.2024.102208

|View full text |Cite

A Janus nanofibrous scaffold integrated with exercise-driven electrical stimulation and nanotopological effect enabling the promotion of tendon-to-bone healing

Qian Zhang,

Jianhua Zhu,

Xiang Fei

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 5 publications

(1 citation statement)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Subsequently, cell cultures were performed for different times (5 and 10 days) on the net patch scaffold and the inside surfaces of the Janus tube to observe the cell migration property (Figure C). The cells mainly migrated and extended along the longitudinal fibers, and then gradually moved to the interlocking fibers on both sides, which has been reported by other researchers as well. − …”

supporting

confidence: 77%

Synergistic Biofilter Tube for Promoting Scarless Tendon Regeneration

Yang,

Xu,

et al. 2024

Nano Lett.

View full text Add to dashboard Cite

Inspired by the imbalance between extrinsic and intrinsic tendon healing, this study fabricated a new biofilter scaffold with a hierarchical structure based on a melt electrowriting technique. The outer multilayered fibrous structure with connected porous characteristics provides a novel passageway for vascularization and isolates the penetration of scar fibers, which can be referred to as a biofilter process. In vitro experiments found that the porous architecture in the outer layer can effectively prevent cell infiltration, whereas the aligned fibers in the inner layer can promote cell recruitment and growth, as well as the expression of tendon-associated proteins in a simulated friction condition. It was shown in vivo that the biofilter process could promote tendon healing and reduce scar invasion. Herein, this novel strategy indicates great potential to design new biomaterials for balancing extrinsic and intrinsic healing and realizing scarless tendon healing.

show abstract

supporting

confidence: 77%

Synergistic Biofilter Tube for Promoting Scarless Tendon Regeneration

Yang,

Xu,

et al. 2024

Nano Lett.

View full text Add to dashboard Cite

show abstract

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Deng,

Luo,

Chen

et al. 2024

Advanced Science

View full text Add to dashboard Cite

Tissue repair and reconstruction are a clinical difficulty. Bioelectricity has been identified as a critical factor in supporting tissue and cell viability during the repair process, presenting substantial potential for clinical application. This review delves into various sources of electrical stimulation and identifies appropriate electrode materials for clinical use. It also highlights the biological mechanisms of electrical stimulation at both the subcellular and cellular levels, elucidating how these interactions facilitate the repair and regeneration processes across different organs. Moreover, specific electrode materials and stimulation sources are outlined, detailing their impact on cellular activity. The future development trends are projected from two perspectives: the optimization of equipment performance and the fulfillment of clinical demands, focusing on the feasibility, safety, and cost‐effectiveness of technologies.

show abstract

Electrospun nanofibrous membranes meet antibacterial nanomaterials: From preparation strategies to biomedical applications

Chen,

Xie,

et al. 2024

Bioactive Materials

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

A Janus nanofibrous scaffold integrated with exercise-driven electrical stimulation and nanotopological effect enabling the promotion of tendon-to-bone healing

Cited by 5 publications

References 46 publications

Synergistic Biofilter Tube for Promoting Scarless Tendon Regeneration

Synergistic Biofilter Tube for Promoting Scarless Tendon Regeneration

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Electrospun nanofibrous membranes meet antibacterial nanomaterials: From preparation strategies to biomedical applications

Contact Info

Product

Resources

About