Theories of human development suggest that, although all cancer patients experience a common set of life disruptions, they experience them differently, focus on different issues, and attach different levels of importance to different aspects of the experience depending on the time in life at which they were diagnosed. During the critical developmental transition from childhood to adulthood, older adolescents and young adults in particular have typical concerns with establishing identity, developing a positive body image and sexual identity, separating from parents, increasing involvement with peers and dating, and beginning to make decisions about careers or employment, higher education, and/or family. Accordingly, cancer-related issues such as premature confrontation with mortality, changes in physical appearance, increased dependence on parents, disruptions in social life and school/employment because of treatment, loss of reproductive capacity, and health-related concerns about the future may be particularly distressing for adolescents and young adults. Psychosocial and behavioral interventions for young adult cancer patients and survivors often involve assisting these individuals in retaining or returning to function in significant social roles, such as spouse, parent, student, worker, or friend. Successful interventions will enable these young people to overcome the detrimental impact of a health crisis and strengthen the internal and external coping resources available to them. Few empirical studies of cancer patients and survivors have distinguished the unique psychosocial outcomes and service needs of adolescents and young adults. Although a sizable body of literature exists for young adult survivors of childhood cancer, the majority of psychosocial oncology research has involved samples of older adult patients or samples inclusive of adult patients across a wide range of ages. Haase and Phillips 1 suggested that there exists a gap in research, in that a common trend of clumping adolescents and young adults, roughly between the ages of 18 and 35 years old, with either pediatric or older adult populations has led to an inadequate understanding of the psychosocial impact of cancer for young people diagnosed in their late teens or young adult years. However, coupled with theories of human development across the lifespan, 2-4 existing research suggests a unique set of psychosocial and developmental issues facing adolescents and young adults with cancer, and has stimulated recent development of support services and specialized care programs for this age-defined population group. [5][6][7][8][9][10][11][12][13] This article serves as a general overview of some of the daily life challenges faced by adolescents and young adults with cancer. Its purpose is to increase awareness around the need for more age-appropriate psychosocial care and research. Critical reviews of emergent literature and more in-depth discussions are reported elsewhere. [14][15][16] Adolescence and young adulthood are developmental stages ma...