In this paper, we research the dynamical evolution and quasinormal modes of nonminimal derivative coupling scalar field in Reissner-Nordström spacetime with a global monopole. We also find that Hawking radiation behavior near the event horizon is similar to the scalar field case. In the whole spacetime, the conclusions show that weak coupling field will affect the dynamical behavior delicately, but the strong coupling constant η results in the deformation of dynamical evolution curve. When η > η c , the black hole system will not be stable. The break from the global monopole also intensely affect the dynamical behavior of this black hole spacetime. Furthermore, the break will promote the instability of the coupling field.