MultiAgent system is designed for distributed environment, and has been proved efficient in the making of clinical decision support. Usually,agents communicate with each other by using messages in a distributed system,hence a well formed and organized message structure might be the key point to get high quality of message transport between different agents.Clinical Document Architecture(CDA),which is a standard for clinical document information exchange ,could convey more standardized clinical information to help physicians make much more accurate clinical decisions.In this paper, a document structure based on CDA is proposed as a message strcture for information exchange between different agents and it is proved flexible and efficient in the clinical information transportation and exchange.Through using the proposed message strcture,agents cooperate with each other much more efficiently ,which could help doctors make much more scientific clinical decisions ,reduce medical errors and then provide higer quality of heathcare.