In this paper, the auxiliary principle technique is extended to study a system of generalized nonlinear mixed variational-like inequalities problem for set-valued mappings without compact values in Banach spaces with p-uniformly convex bidual spaces. First, the existence of the solutions of the related auxiliary problem is proved. Then, a new iterative algorithm based on the system of auxiliary variational inequalities is constructed. Finally, both the existence of the solutions of the original problem and the convergence of the iterative sequences generated by the algorithm are proved. And we also present a numerical example to demonstrate the result. Our results improve and extend some known results.