A laboratory study evaluating the pH of various modern root canal filling materials

Pawińska, Małgorzata; Szczurko, Grzegorz; Kierklo, Anna; Sidun, Jarosław

doi:10.17219/acem/60440

Cited by 6 publications

(21 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The use of endodontic sealers with antibacterial activity has been effective in the clearance of persistent microorganisms [1] favoring periapical tissue repair [2]. Calcium hydroxide releases hydroxyl ion, providing an alkaline pH and exerting an antibacterial effect followed by periapical tissue repair [3,4]. Among several calcium hydroxide-based root canal filling materials, Sealapex (Sybron Endo, Glendora, CA, USA) is considered biocompatible [5].…”

Section: Introductionmentioning

confidence: 99%

Physical Properties, Antimicrobial Activity and In Vivo Tissue Response to Apexit Plus

et al. 2020

View full text Add to dashboard Cite

We investigated the physical properties, antimicrobial activity, and tissue reaction to Apexit Plus in comparison to Sealapex. Flow, radiopacity, setting time, and solubility were evaluated in each material. The antimicrobial activity against Enterococcus faecalis was performed. Polyethylene tubes containing Apexit Plus or Sealapex, and without material (control group) were implanted into the subcutaneous tissue of rats. At 7, 15, 30, and 60 days of implantation, the specimens were paraffin-embedded and the number of inflammatory cells (ICs) and the amount of birefringent collagen (BC) were quantified. The von Kossa reaction followed by immunohistochemistry for detection of alkaline phosphatase (ALP) was also performed. Statistical analysis was performed with ANOVA and Tukey test (p ≤ 0.05). The flow value of Apexit Plus was greater than Sealapex, whereas the radiopacity (3.44 mm Al) was lower than Sealapex (6.82 mm Al). Apexit Plus showed lower solubility and shorter initial and final setting (p < 0.0001), whereas the antimicrobial activity was significantly greater than Sealapex. Although the number of ICs was higher in Apexit Plus (p = 0.0009) at 7 days, no significant difference was detected between Apexit Plus and Sealapex at 15, 30, and 60 days. All groups showed higher values for BC in the capsules over time. ALP-immunolabelled cells were observed, mainly around von Kossa-positive structures, either in the capsules of Apexit Plus or Sealapex. Therefore, our results revealed that Apexit Plus exhibited a greater effectiveness against Enterococcus faecalis and better physical properties than Sealapex, except for the radiopacity. In vivo findings indicate that Apexit Plus is biocompatible and presents potential bioactivity in the subcutaneous tissue.

show abstract

Section: Introductionmentioning

confidence: 99%

Physical Properties, Antimicrobial Activity and In Vivo Tissue Response to Apexit Plus

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Im lepsze właściwości alkalizujące materiału, tym większe jego właściwości przeciwbakteryjne oraz przeciwgrzybicze [35,36,37,38]. W związku z tym należy przypuszczać, iż oceniane w badaniu uszczelniacze: BioRoot RCS, Total Fill BC Sealer, Well-Root ST oraz w mniejszym stopniu GuttaFlow bioseal oraz MTA Fillapex powinny wykazywać działanie przeciwdrobnoustrojowe.…”

unclassified

Właściwości alkalizujące wybranych krzemianowo-wapniowych uszczelniaczy kanałowych. Badanie in vitro

Reszka

Kucharski

Klimowicz

et al. 2018

Pomeranian J of Life Sci

View full text Add to dashboard Cite

Introduction: The aim of this in vitro study was to assess the pH values of selected calcium-silicate root canal sealers in comparison with AH Plus resin-based root canal sealer.Materials and methods: Six root canal sealers were included in this study: BioRoot RCS (Septodont, France), GuttaFlow bioseal (Coltėne/Whaledent, Switzerland), MTA Fillapex (Angelus, Brazil), Total Fill BC Sealer (FKG, Switzerland), Well-Root ST (Vericom, Korea) and AH Plus (Dentsply, DeTrey, Germany). Materials samples (n = 6) were placed in dishes and immersed in 10 mL of distilled water (pH = 6.8). After 1, 3, 24, 48, 72, 168, 336 and 504 hrs, water pH was determined with a pH meter calibrated with a solution of known pH. Data were statistically analyzed using Student-t test (p < 0.05).Results: There were differences in the water pH between the materials tested. The highest water pHs were exhibited by Total Fill BC Sealer, Well-Root ST and BioRoot RCS (pH ~12), followed by GuttaFlow bioseal (pH ~10.5) and MTA Fillapex (pH ~9). The lowest pH was shown by AH Plus (pH ~8).Conclusions: All calcium-silicate root canal sealers studied are able to elevate the pH level, which could have biological and antimicrobial effects. The AH Plus root canal sealer has poor alkalizing properties.

show abstract

“…The effects of endodontic treatment depend mainly on decontamination and complete obturation of the root system of the teeth. [1][2][3][4][5][6][7][8][9][10] During the mechanical preparation of root canals, a smear layer is created. [1][2][3][4][5][6][7] Its role in endodontic treatment is still debated.…”

Section: Introductionmentioning

confidence: 99%

“…It is supposed that the smear layer should be removed after the mechanical preparation of root canals, because the sealing effect of canal obturation can be marred as a result of changes in the volume of the smear layer, and because the smear layer prevents access to the dentinal tubules, where pathogens can be located. [6][7][8] Dissolution of the smear layer opens the dentinal tubules and increases the permeability of dentin, as a result of which antiseptic solutions and sealers can penetrate the dentinal tubules to neutralize and seal in microorganisms. 8 Sodium hypochlorite (NaOCl; for the dissolution of organic components) and chelating agents (for the dissolution of inorganic components) are used to remove the smear layer.…”

Section: Introductionmentioning

confidence: 99%

“…[6][7][8] Dissolution of the smear layer opens the dentinal tubules and increases the permeability of dentin, as a result of which antiseptic solutions and sealers can penetrate the dentinal tubules to neutralize and seal in microorganisms. 8 Sodium hypochlorite (NaOCl; for the dissolution of organic components) and chelating agents (for the dissolution of inorganic components) are used to remove the smear layer. Commonly used chelating agents include EDTA (in the form of disodium salt of ethylenediaminetetraacetic acid) and citric acid (CA).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The effects of alternate irrigation of root canals with chelating agents and sodium hypochlorite on the effectiveness of smear layer removal

Wilkoński¹,

Jamróz-Wilkońska²,

Zapotoczny³

et al. 2020

Adv Clin Exp Med

View full text Add to dashboard Cite

Background. After the mechanical preparation of a root canal, the canal walls are covered with a smear layer. In order to deeply clean the dentinal tubules, removal of the smear layer is recommended. There is no consensus on the length of time of rinsing with chelating agents or irrigation with alternating chelating agents and sodium hypochlorite (NaOCl). Objectives. The aim of the study was to evaluate the effectiveness of smear layer removal using 4 irrigation protocols. Material and methods. We prepared 42 straight root canals to size ISO40/04 and assigned them into 4 study groups (n = 10) and a control group (n = 2). The root canals were irrigated as follows: in the control group, 180 s with 5.25% NaOCl; in group 1, 60 s with 40% citric acid (CA) and 120 s with NaOCl; in group 2, 120 s with CA and 120 s with NaOCl; in group 3, 30 s CA, 30 s with NaOCl, 30 s CA and 120 s with NaOCl; and in group 4, 60 s with CA, 30 s with NaOCl, 60 s with CA, and 120 s with NaOCl. The roots were split longitudinally and the root canals were observed under ×200-500 magnification. The root canal walls were analyzed in areas 2 mm, 6 mm and 10 mm from the apex. Results. In the apical and medial sections, the best effects were achieved in groups 3 and 4. In coronal sections, no significant differences between experimental groups were found. Conclusions. Within the limitations of this study, it can be concluded that irrigation with alternating NaOCl and CA was the most effective at smear layer removal, regardless of the irrigation time.

show abstract

A laboratory study evaluating the pH of various modern root canal filling materials

Cited by 6 publications

References 23 publications

Physical Properties, Antimicrobial Activity and In Vivo Tissue Response to Apexit Plus

Physical Properties, Antimicrobial Activity and In Vivo Tissue Response to Apexit Plus

Właściwości alkalizujące wybranych krzemianowo-wapniowych uszczelniaczy kanałowych. Badanie in vitro

The effects of alternate irrigation of root canals with chelating agents and sodium hypochlorite on the effectiveness of smear layer removal

Contact Info

Product

Resources

About