Using dropsonde data and a flux–profile method, this study investigates the drag coefficient (Cd)–wind speed relationship within different radius ranges. The results show a systematic decrease of friction velocity u* from the range of R/RMW > 1.05 to that of R/RMW < 0.95 (R is the radial location of a dropsonde profile, and RMW is the radius of maximum wind), and the reduction is 5~25% for different wind speeds. Further, within the ranges of either R/RMW > 1.05 or R/RMW < 1.05, a clear feature of “roll-off” at about 35 m s−1 can be obtained. However, the roll feature becomes vague in the ranges of R/RMW < 0.95, R/RMW < 0.85, and R/RMW < 0.75, indicating the TC dynamics within and near RMW play a role in affecting the flux–profile relationship. Even more, Cd of R < 0.75RMW deviates significantly from the Cd of R < 0.85RMW and R < 0.95RMW, while the deviation between R < 0.85RMW and R < 0.95RMW is much smaller. Especially when 10 m winds exceed 40 m s−1, u* of R < 0.75RMW is significantly larger than that of R < 0.85RMW. This phenomenon is also linked to the TC dynamics (e.g., the large radial gradients of winds and the drastic vertical variation of the bulk Richardson number), but the speculation needs to be verified in future study.