A Lanthanide MOF Thin‐Film Fixed with Co₃O₄ Nano‐Anchors as a Highly Efficient Luminescent Sensor for Nitrofuran Antibiotics

Abstract

Nitrofurans are a group of widely used veterinary antibiotics, which have been banned due to antibiotics pollution. Development of a rapid and effective method for the detection of nitrofuran antibiotics (NFAs) is an important challenge. Herein, we designed a chemical sensor based on a thin-film composed of the lanthanide metal-organic framework (Ln-MOF) {[Eu (BCA) (H O)(DMF) ]⋅0.5DMF⋅H O} (Eu-BCA, in which BCA is 2,2'-biquinoline-4,4'-dicarboxylate) coated on a cost-effective stainless steel wire mesh (SSWM) by Co O nano-anchor fixation method. The MOF coatings were well adhered to the SSWM, resulting in a three-dimensional porous, flexible, and processable sensor. The structure of the as-prepared MOF thin-film was confirmed by powder X-ray diffraction (PXRD), and the surface morphology was examined by scanning electron microscopy (SEM). Significantly, the Eu-BCA thin-film was highly selective and sensitive to NFAs, and yet remained unaffected by other common antibiotics that may be present. The limits of detection for nitrofurantoin (NFT) and nitrofurazone (NFZ) are 0.21 and 0.16 μm, respectively. NFAs were also successfully detected in water from the Pearl River in Guangzhou, and from bovine serum samples. Hence, the reported Ln-MOF thin-film is a promising sensor for the detection of NFAs, thereby helping to protect human beings from all manner of hazards that arise from the abuse of antibiotics in livestock breeding.

A novel nano‐size lanthanum metal–organic framework based on 5‐amino‐isophthalic acid and phenylenediamine: Photoluminescence study and sensing applications

“…It can be observed from the spectra a broad photoluminescent emission with enhanced intensity characteristic of La (III) complexes with f‐d transitions . Also, the fluorescent behavior of the La‐MOF materials can be attributed to π –π* and π‐n molecular orbital transitions within the aromatic rings of the carboxylate and diamine ligands or due to ligand‐to‐metal charge transfer . (Figure S9, supplementary material) shown the excitation and emission spectra of the La‐MOF (M1).…”

A Water‐Stable Uranyl Organic Framework as a Highly Selective and Sensitive Bifunctional Luminescent Probe for Fe3+ and Tetracycline Hydrochloride

“…However, it is difficult to metabolize after entering humans and animals, leading to the growth and spread of resistant bacteria and drug‐resistant genes, which have serious impacts on ecosystems. In recent years, the abuse of antibiotic drugs has exacerbated this phenomenon . At the same time, iron as an essential trace element of the human body is an important part of hemoglobin, involved in the transportation and storage of oxygen.…”

“…Antibiotics are widelyu sed to treat bacterial infections in humans and animals. [1][2][3][4] However,i ti sd ifficult to metabolize after entering humansa nd animals, leading to the growth and spread of resistant bacteria and drug-resistant genes, which have seriousi mpactso ne cosystems. In recent years, the abuse of antibiotic drugs has exacerbatedt his phenomenon.…”

“…In recent years, the abuse of antibiotic drugs has exacerbatedt his phenomenon. [4][5][6] At the same time, iron as an essential trace element of the human body is an important part of hemoglobin, involved in the transportation and storage of oxygen. Many enzymes and immune system compounds contain iron.…”

Synthesis, Structure and Sensing Property of Novel Zinc(II) Framework with Mixed 3,3′,5,5′‐Tetra(1H‐imidazol‐1‐yl)biphenyl and 2,6‐Naphthalenedicarboxylate Ligands

“…[1] However, with increasing use or even abuse of antibiotics nowadays it becomes a problem for the antibiotics as environmental contaminants. [2] Therefore, it is essential for researchers to develop methods and devices that can detect antibiotics selectively and sensitively. To date, fluorescent chemical sensing has been proved to be powerful for fast and efficient detecting antibiotics.…”