A large and aggressive fibromatosis in the axilla: a rare case report and review of the literature

Duan, Mingyue; Hua, Xin; Wang, Keren; Niu, Chen; Jiang, Chengwei; Zhang, Lijuan; Ezzat, Shereen; Zhang, Le

doi:10.2147/ott.s165209

Cited by 6 publications

(8 citation statements)

References 19 publications

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“…The 18F-FDG PET/CT of our case revealed an axillary locally hypermetabolic lesion, and that was considered as lymph node metastasis. We listed some representative reported cases that are same or similar to our case in Table 1 (4)(5)(6)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31), and the sonographic and radiological manifestations of these cases could be compared intuitively to give helpful information for clinicians. Of the 24 cases listed, the clinical and imaging manifestations are various and the masses were usually misdiagnosed as carcinoma, Prior studies have reported that mammography, ultrasound and MRI were used extensively.…”

Section: Discussionmentioning

confidence: 95%

“…It is helpful for surgeons to determine the surgical region preoperatively to make sure the margins negative (17). Thus breast MRI is almost essential for assessing soft-tissue mass and guiding clinical treatment (18). PET/CT is not the necessary examination for aggressive fibromatosis, but it could provide more valuable information about the pathological metabolic activity and distant metastasis of tumor.…”

Section: Discussionmentioning

confidence: 99%

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Aggressive breast fibromatosis with axillary accessory breast mastitis mimicking carcinoma: a case report

Huang¹,

Shao²,

Shi³

et al. 2021

Transl Breast Cancer Res

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Aggressive fibromatosis, also referred to as desmoid-type fibromatosis or desmoid tumor, is an uncommon locally invasive tumor with a high local recurrence rate. It rarely occurs in the breast and the etiology of aggressive breast fibromatosis is still unknown but may be related to previous mammary trauma or surgery. Preoperative diagnosis of aggressive breast fibromatosis is still a challenge for clinicians. The optimal treatment for the disease is still controversial, but wide surgical excision with negative margins is considered the standard option. We report a 28-year-old woman of aggressive breast fibromatosis accompanied with accessory breast mastitis in her ipsilateral axilla. The lesions imitated breast carcinoma with axillary lymph node metastasis due to their similar clinical and imaging manifestations. Her mammary mass finally underwent wide surgical excision, and negative margins were confirmed during the surgery. To our knowledge, this is an extremely rare case accompanied with axillary accessory breast mastitis and will contribute to the management of aggressive breast fibromatosis.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Aggressive breast fibromatosis with axillary accessory breast mastitis mimicking carcinoma: a case report

Huang¹,

Shao²,

Shi³

et al. 2021

Transl Breast Cancer Res

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“…Areas with more uptake are likely to represent cellularity and high mitotic areas. [ 4 5 6 ] As fibromatosis is 10% familial, 18 F-FDG PET/CT can help rule out multifocal involvement or cutaneous involvement or intra-/extra-abdominal desmoids and look for colonic polyposis. It should be noted that the SUV values are not high in all malignant tumors and depend on many factors such as blood sugar, body mass index, dose injected, time between injection and scan, and tumor differentiation.…”

Section: Discussionmentioning

confidence: 99%

Fibromatosis with aggressive demeanor: Benign impersonator of malignancy

et al. 2021

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Fibromatosis or desmoid fibromatosis is a rare benign neoplasm and develops commonly in the abdominal wall, abdominal cavity, or extra-abdominal sites. The mainstay of treatment is surgery. Chemotherapy and radiotherapy are preferred in cases of inoperable/relapse or a multifocal disease. Hereby, we report a case of fibromatosis arising in the left popliteal fossa, proven by histopathology and immunohistochemistry. Local excision of the mass was performed. The patient was asymptomatic for 6 months, after which she complained of difficulty in walking. Clinical evaluation elicited recurrence in the surgical bed. In spite of the surgical excision with tumor-free margins, recurrence was seen within a span of 6 months. 18 F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) was done to rule out multifocal disease and to define the extent of relapse. Although magnetic resonance imaging provides an excellent soft-tissue resolution to delineate the disease, 18 F-FDG PET/CT is an important and supplementary tool which aids in the management of fibromatosis.

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“…In our case, intra-abdominal desmoid tumor was diagnosed based on histological findings and immunohistochemical staining. Only expression of beta-catenin is positive in desmoid tumor immunohistochemically, 5 which helps with diagnosis; however, the lack of specific markers for desmoid tumor requires diagnosis by exclusion. In preoperative diagnosis, the desmoid tumor was regarded as local recurrence of RCC based on FDG accumulation in PET/CT.…”

Section: Discussionmentioning

confidence: 99%

Intra-abdominal desmoid tumor mimicking local recurrence of renal cell carcinoma after laparoscopic partial nephrectomy

Hara

Fujii

Ohira

et al. 2019

Urology Case Reports

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A 64-year-old man had an intra-abdominal mass that was detected in a follow-up examination after laparoscopic partial nephrectomy for renal cell carcinoma (RCC). CT showed an enhanced mass of 2.5-cm diameter near the right kidney, where partial nephrectomy had been performed. Local recurrence of RCC with duodenum invasion was suspected, and excision was performed. The final pathological diagnosis of desmoid tumor differed from the preoperative diagnosis. Therefore, we report this case as a rare example of intra-abdominal desmoid tumor mimicking local recurrence of RCC. To our knowledge, this is the first report of intra-abdominal desmoid tumor after laparoscopic partial nephrectomy.

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A large and aggressive fibromatosis in the axilla: a rare case report and review of the literature

Cited by 6 publications

References 19 publications

Aggressive breast fibromatosis with axillary accessory breast mastitis mimicking carcinoma: a case report

Aggressive breast fibromatosis with axillary accessory breast mastitis mimicking carcinoma: a case report

Fibromatosis with aggressive demeanor: Benign impersonator of malignancy

Intra-abdominal desmoid tumor mimicking local recurrence of renal cell carcinoma after laparoscopic partial nephrectomy

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