A large, benign prostatic cyst presented with an extremely high serum prostate-specific antigen level

Abstract

SUMMARYWe report a case of a patient who presented with an extremely high serum prostate specific antigen (PSA) level and underwent radical prostatectomy for presumed prostate cancer. Surprisingly, the whole mount prostatectomy specimen showed only small volume, organ-confined prostate adenocarcinoma and a large, benign intraprostatic cyst, which was thought to be responsible for the PSA elevation. BACKGROUND

Prostatic cyst: A rare entity with differential diagnostic challenges in urology - A case report

“…Moreover, Han-Kuang Chen and al. 5 reported the case of a 61-year-old man who presented with a PSA of 79 ng/mL and underwent radical prostatectomy for suspected prostate cancer and in whom the pathology results surprisingly showed only small-volume, organ-confined tumors and a large benign intraprostatic cyst. The cyst was unilocular and non-hemorrhagic.…”

Extremely Elevated Prostate-Specific Antigen in Acute Prostatitis: A Case Report

“…Generally, they are seen at a PSA level of less than 50 ng/mL [ 2 ]. A large, benign prostatic cyst was reported to be associated with a PSA level of 79 ng/mL [ 5 ]. Also, high levels of PSA were found in patients with cardiogenic shock without any prostate disease as reported by Fernandez-Galan et al [ 6 ].…”

Prostatic cyst in general practice

“…In addition, some large benign prostatic cysts presented with PSA elevation, needing the differential diagnosis. [ 2 , 3 ] The differential diagnoses include Mullerian duct cysts, bladder diverticulum, teratoma, seminal vesicle cyst, epididymal cyst, and Wolffian duct cyst. [ 12 ] Once GPs have difficulty for the differentiation for patients with progressive symptoms, timely referral should be performed.…”

“…[ 1 ] It is often asymptomatic and found accidentally with abdominal ultrasound, computerized tomography (CT), or magnetic resonance imaging (MRI). As some large prostatic cysts would have high level of serum prostate-specific antigen (PSA), [ 2 , 3 ] it should be differentiated from other disorders such as prostatic neoplasm. Although it has been reported by some urological specialists, to our knowledge, this is the first case report and literature review that conclude how to do when a general practitioner (GP) encountered patients with prostatic cyst.…”