A lifestyle intervention for older schizophrenia patients with diabetes mellitus: A randomized controlled trial

McKibbin, Christine L.; Patterson, Thomas L.; Norman, Gregory J.; Patrick, Kevin; Jin, Hua; Roesch, Scott C.; Mudaliar, Sunder; Barrio, Concepción; O’Hanlon, Kathleen; Griver, Kay; Sirkin, A'verria; Jeste, Dilip V.

doi:10.1016/j.schres.2006.05.010

Cited by 171 publications

(226 citation statements)

References 33 publications

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“…However, the average weight loss in these ten studies varied by study design. The mean weight loss for the three single-group studies (20,31,24) was 8.2±5 pounds, whereas the three quasi-experimental studies (24,25,28) and four randomized controlled trials (21–23,35) showed more modest average weight loss (6.2±.4 pounds and 3.4±2.9 pounds, respectively). The mean for the randomized controlled trials reviewed falls below the mean weight loss reported in meta-analyses of randomized controlled trials of lifestyle interventions tested in the general population, which was eight to 11 pounds (44,45).…”

Section: Discussionmentioning

confidence: 91%

“…Four studies did not specify medication inclusion criteria, but they did enumerate in a general manner (for example, second-generation antipsychotic medications) the type of medications that participants were taking at the time of enrollment (18,23,30,33). The rest of the studies specified medication inclusion criteria that were either restricted to monotherapy with one antipsychotic medication at the time of enrollment (26,27) or combination treatment of one antipsychotic with other psychotropics (16,20,21,24,25,31,32,36).…”

Section: Resultsmentioning

confidence: 99%

“…Intervention formats featured individual sessions (29) and group sessions (16,17,19,21,23,26–28,31–34,36,37), with some integrating both approaches (20,22,24,25,38). Interventions were delivered by a range of staff, including registered nurses, exercise physiologists, registered dieticians, trained fitness instructors, case managers, and master's- and doctoral-level health care practitioners.…”

Section: Resultsmentioning

confidence: 99%

“…Thirteen studies assessed whether lifestyle interventions improved risk factors for metabolic syndrome, including systolic blood pressure (sBP) and diastolic blood pressure (dBP), heart rate, blood glucose, triglycerides, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol, and waist and hip circumference (19–21,23,24,26–28,30,33,34,36,38). Seven studies reported statistically significant improvements on at least one of these risk factors.…”

Section: Resultsmentioning

confidence: 99%

“…These seven studies used a range of methodologies. Two were single-group studies (20,28), two were quasi-experimental studies (24,28), and three were randomized controlled trials (19,21,23). These studies reported positive effects on sBP and dBP, blood glucose and triglyceride levels, and central adiposity.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Lifestyle Interventions for Adults With Serious Mental Illness: A Systematic Literature Review

Cabassa¹,

Ezell²,

Lewis‐Fernández³

2010

Psychiatric Services

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Objective The promotion of healthy lifestyles among persons with serious mental illness is an integral part of their recovery. The aims of this systematic literature review were to rate the methodological quality of lifestyle intervention outcome studies for persons with serious mental illness, summarize intervention strategies, examine physical health outcomes, and evaluate the inclusion of racial and ethnic minority groups in these studies. Methods Electronic bibliographic database searches were performed to locate studies conducted in the United States. Articles written in English and published in peer-reviewed journals between 1980 and 2009 were included. The authors used a standardized instrument to rate studies' methodological quality. Results Twenty-three articles were reviewed. Based on studies' methodological quality, three levels of evidence were found: single-group reports, quasi-experimental studies, and randomized controlled trials. Most interventions used behavioral techniques to improve dietary habits and increase physical activity. Twelve studies reported significant improvements in either weight loss or metabolic syndrome risk factors associated with receiving a lifestyle intervention. Persons from racial and ethnic minority groups were underrepresented, especially Hispanics and Asian Americans. Only one study included non–English-speaking participants. Conclusions Lifestyle interventions adapted to persons with serious mental illness show promise in reducing weight loss and some risk factors for metabolic syndrome. The under-representation of persons from racial or ethnic minority groups in this literature limits its generalizability. Implications for research and practice are discussed.

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