A 45-year-old male with renal cell carcinoma secondary to von-Hippel Lindau (VHL) disease presented for radiofrequency ablation (RFA) of kidney tumors. Due to his prior history of several partial nephrectomies and limited renal reserve, RFA was chosen because of its relatively nephronsparing nature. A laser guidance device was used to help guide probe placement in an attempt to reduce procedure time and improve targeting accuracy. The device was successful at guiding needle placement, as both tumors were located with a single pass. Follow-up CT scan confirmed accurate needle placement, showing an area of coagulation necrosis covering the previously seen tumor.
KeywordsRadiofrequency ablation; Laser guidance; Renal cell carcinoma; von-Hippel Lindau disease Navigation and guidance devices for CT-guided interventions have been relatively underutilized, however, they show promise for effectively and accurately assisting needle or probe placement. Multiple systems and techniques have been developed to assist CT-guided procedures [5][6][7][8][9], varying from the complex (robotics) [1], to the simple fluid-filled disk, to approximate planned needle angulations [2].Radiofrequency ablation (RFA) is becoming broadly available in the oncology community, and is being studied for kidney tumors with some degree of success. We have performed nearly 200 kidney tumor ablations, and we often rely upon nearby landmarks for accurate needle angle selection to treat radiographically occult tumors. Laser guidance was used to assist in RFA in a kidney tumor that was difficult to visualize by CT scan without contrast. Local ablative therapies rely upon extreme accuracy for successful outcomes. The device (SimpliCT, NeoRad AS, Norway) is free standing, portable, and independent of the CT gantry. It consists of a laser source mounted on an L-shaped track, which stands on a 3-wheel lockable base (Fig. 1). Laser guidance simplified radiofrequency probe angulation implementation, and also facilitated probe repositioning for a second burn, according to a treatment plan developed with pretreatment CT. The authors have no commercial interest in the device.
Case ReportA 45-year-old male with a history of von Hippel-Lindau disease presented for radiofrequency ablation of 2 left-sided kidney tumors. VHL is an autosomal dominant disorder, characterized by the development of both benign and malignant tumors [3]. This patient had bilateral renal cell carcinoma, and had undergone a left partial nephrectomy in 1995, and a right partial nephrectomy in 1999. During a follow-up hospitalization in 2000, he was found to have regrowth of tumor in both kidneys. Percutaneous RFA of the left-sided lesions was attempted at that time, but the procedure was aborted secondary to inadequate visualization of the tumors.