Abstract. The security of sensitive data and the safety of control signal are two core issues in industrial control system (ICS). However, the prevalence of USB storage devices brings a great challenge on protecting ICS in those respects. Unfortunately, there is currently no solution especially for ICS to provide a complete defense against data transmission between untrusted USB storage devices and critical equipment without forbidding normal USB device function. This paper proposes a trust management scheme of USB storage devices for ICS (TMSUI). By fully considering the background of application scenarios, TMSUI is designed based on security chip to achieve authoring a certain USB storage device to only access some exact protected terminals in ICS for a particular period of time. The issues about digital forensics and revocation of authorization are discussed. The prototype system is finally implemented and the evaluation on it indicates that TMSUI effectively meets the security goals with high compatibility and good performance.