2024
DOI: 10.1080/19491034.2024.2310452
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A lineage-specific protein network at the trypanosome nuclear envelope

Erin R. Butterfield,
Samson O. Obado,
Simon R. Scutts
et al.

Abstract: The nuclear envelope (NE) separates translation and transcription and is the location of multiple functions, including chromatin organization and nucleocytoplasmic transport. The molecular basis for many of these functions have diverged between eukaryotic lineages. Trypanosoma brucei , a member of the early branching eukaryotic lineage Discoba, highlights many of these, including a distinct lamina and kinetochore composition. Here, we describe a cohort of proteins interacting with both t… Show more

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