A linearization of the parameters in the logistic function: Curve fitting radioimmunoassays

Data obtained from routine analytical radioimmunoassays were processed using five curve-fitting procedures, viz. ‘Amersham’, single binding site, four parameter logistic, a linear logit-log and a polynomial logit-log. The polynomial logit-log procedure gave the best fit, but this was probably due to the inherent flexibility of this curve-fitting process since the analytical precision achieved with it was no better than what was obtained with most of the other procedures. A limited study failed to show that statistical weighting of data before curve fitting had any practical advantage.

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A Comparison of Five Curve-Fitting Procedures in Radioimmunoassay

Nisbet

Owen

Ward

1986

Ann Clin Biochem

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A linearization of the parameters in the logistic function: Curve fitting radioimmunoassays

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A Comparison of Five Curve-Fitting Procedures in Radioimmunoassay

A Comparison of Five Curve-Fitting Procedures in Radioimmunoassay

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