2020
DOI: 10.1101/2020.03.09.976043
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A lipid atlas of human carotid atherosclerosis

Abstract: 22tissue type, and to demonstrate a clear co-localization between plaque features and specific lipid classes 37 and individual lipid molecules in high-risk atherosclerotic plaques. 38

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(2 citation statements)
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“…Indeed, the molecular characterization of lipids has revealed how sphingolipids, ceramides, and lysophospholipids are among the lipid classes playing a major role in atherosclerosis formation and progression. [7][8][9] Only few papers have deeply evaluated the lipid composition of atherosclerotic plaques in humans [10,11] and if-and to which extent-dietary or pharmacological treatments can modify the plaque lipidome. How these modifications can affect atherosclerosis, is still an open question.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Indeed, the molecular characterization of lipids has revealed how sphingolipids, ceramides, and lysophospholipids are among the lipid classes playing a major role in atherosclerosis formation and progression. [7][8][9] Only few papers have deeply evaluated the lipid composition of atherosclerotic plaques in humans [10,11] and if-and to which extent-dietary or pharmacological treatments can modify the plaque lipidome. How these modifications can affect atherosclerosis, is still an open question.…”
Section: Introductionmentioning
confidence: 99%
“…Only few papers have deeply evaluated the lipid composition of atherosclerotic plaques in humans [ 10,11 ] and if—and to which extent—dietary or pharmacological treatments can modify the plaque lipidome. How these modifications can affect atherosclerosis, is still an open question.…”
Section: Introductionmentioning
confidence: 99%