2022
DOI: 10.1186/s43591-022-00032-4
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A living tool for the continued exploration of microplastic toxicity

Abstract: Throughout the past decade, many studies have reported adverse effects in biota following microplastic exposure. Yet, the field is still emerging as the current understanding of microplastic toxicity is limited. At the same time, recent legislative mandates have required environmental regulators to devise strategies to mitigate microplastic pollution and develop health-based thresholds for the protection of human and ecosystem health. The current publication rate also presents a unique challenge as scientists,… Show more

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Cited by 36 publications
(20 citation statements)
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“…32 The toxicity databases, tools to estimate particle characteristics, align toxicity studies, screen studies for quality criteria, and more were made freely available in an open-source and open-data repository utilizing an Rshiny web application called the Toxicity of Microplastics Explorer ("ToMEx") (https:// github.com/SCCWRP/aq_mp_tox_shiny). 31 Additionally, ToMEx allows users to upload additional published toxicity datatherefore enabling rapid and real-time meta-analyses and assessments of risk and reducing burdens of future assessments. 31 To inform California's management of MPs in aquatic ecosystems, the health effects workshop devised a framework that includes four risk-based threshold tiers each with increasing levels of critical actions recommended to be undertaken by the appropriate regulatory bodies, ranging from low concernprompting additional investigative monitoringto the highest level of concernpollution control measures.…”
Section: Assessing Hazards Of Microplastics In Aquatic Ecosystemsmentioning
confidence: 99%
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“…32 The toxicity databases, tools to estimate particle characteristics, align toxicity studies, screen studies for quality criteria, and more were made freely available in an open-source and open-data repository utilizing an Rshiny web application called the Toxicity of Microplastics Explorer ("ToMEx") (https:// github.com/SCCWRP/aq_mp_tox_shiny). 31 Additionally, ToMEx allows users to upload additional published toxicity datatherefore enabling rapid and real-time meta-analyses and assessments of risk and reducing burdens of future assessments. 31 To inform California's management of MPs in aquatic ecosystems, the health effects workshop devised a framework that includes four risk-based threshold tiers each with increasing levels of critical actions recommended to be undertaken by the appropriate regulatory bodies, ranging from low concernprompting additional investigative monitoringto the highest level of concernpollution control measures.…”
Section: Assessing Hazards Of Microplastics In Aquatic Ecosystemsmentioning
confidence: 99%
“…31 Additionally, ToMEx allows users to upload additional published toxicity datatherefore enabling rapid and real-time meta-analyses and assessments of risk and reducing burdens of future assessments. 31 To inform California's management of MPs in aquatic ecosystems, the health effects workshop devised a framework that includes four risk-based threshold tiers each with increasing levels of critical actions recommended to be undertaken by the appropriate regulatory bodies, ranging from low concernprompting additional investigative monitoringto the highest level of concernpollution control measures. 10 Using the best available data, risk-based thresholds were derived using species sensitivity distributions 10a statistical approach which is commonly used by regulatory authorities in many jurisdictions globally to set limits in the environment.…”
Section: Assessing Hazards Of Microplastics In Aquatic Ecosystemsmentioning
confidence: 99%
See 2 more Smart Citations
“…(see [8]). These thresholds could be guided by metaanalyses of the existing literature [22], or future toxicity tests designed to better answer these questions relevant to how the multidimensionality informs risk. An example of how this may look is in Fig.…”
Section: Applying the Risk Value To A Risk Assessmentmentioning
confidence: 99%