A longitudinal study of neuropsychological change in individuals with Parkinson's disease

Azuma, Tamiko; Cruz, Robyn Flaum; Bayles, Kathryn A.; Tomoeda, Cheryl K.; Montgomery, Erwin B.

doi:10.1002/gps.1022

Cited by 60 publications

(40 citation statements)

References 31 publications

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“…Some studies have indicated that a verbal fluency decline is associated with PD [36]. Although this deficit might appear to be a potential confound in our study, we found that when performing the COWAT, the subjects with RHO did not differ from those with LHO but when examining verbal creativity these groups did differ.…”

Section: Discussioncontrasting

confidence: 78%

Creativity in Parkinson's disease as a function of right versus left hemibody onset

Drago

Foster

Skidmore

et al. 2009

Journal of the Neurological Sciences

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Section: Discussioncontrasting

confidence: 78%

Creativity in Parkinson's disease as a function of right versus left hemibody onset

Drago

Foster

Skidmore

et al. 2009

Journal of the Neurological Sciences

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“…Severe damage to the autonomic, limbic, and somatomotor systems that began in the presymptomatic phase can become compounded by supervening functional deficits on the part of the cerebral cortex (Azuma et al 2003).…”

Section: Stages 5 Andmentioning

confidence: 99%

Stages in the development of Parkinson’s disease-related pathology

et al. 2004

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The synucleinopathy, idiopathic Parkinson's disease, is a multisystem disorder that involves only a few predisposed nerve cell types in specific regions of the human nervous system. The intracerebral formation of abnormal proteinaceous Lewy bodies and Lewy neurites begins at defined induction sites and advances in a topographically predictable sequence. As the disease progresses, components of the autonomic, limbic, and somatomotor systems become particularly badly damaged. During presymptomatic stages 1-2, inclusion body pathology is confined to the medulla oblongata/pontine tegmentum and olfactory bulb/anterior olfactory nucleus. In stages 3-4, the substantia nigra and other nuclear grays of the midbrain and forebrain become the focus of initially slight and, then, severe pathological changes. At this point, most individuals probably cross the threshold to the symptomatic phase of the illness. In the end-stages 5-6, the process enters the mature neocortex, and the disease manifests itself in all of its clinical dimensions.

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“…Executive function has been reported to be most susceptible to progression [30]. However, it is unknown, which brain regions relate to the functional decline.…”

Section: Longitudinal Changes In Sequence Learningmentioning

confidence: 99%

Functional imaging of sequence learning in Parkinson's disease

Carbon

Eidelberg

2006

Journal of the Neurological Sciences

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A longitudinal study of neuropsychological change in individuals with Parkinson's disease

Abstract: Consistent with previous studies, executive function tasks were those most susceptible to disease progression.

Cited by 60 publications

References 31 publications

Creativity in Parkinson's disease as a function of right versus left hemibody onset

Creativity in Parkinson's disease as a function of right versus left hemibody onset

Stages in the development of Parkinson’s disease-related pathology

Functional imaging of sequence learning in Parkinson's disease

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