A low-fouling electrochemical biosensor based on BSA hydrogel doped with carbon black for the detection of cortisol in human serum

Yu, Xiaohang; Meng, Weichen; Li, Yang; Luo, Xiliang

doi:10.1016/j.aca.2024.342645

Analytica Chimica Acta

2024

DOI: 10.1016/j.aca.2024.342645

|View full text |Cite

A low-fouling electrochemical biosensor based on BSA hydrogel doped with carbon black for the detection of cortisol in human serum

Xiaohang Yu,

Weichen Meng,

Yang Li

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

A Wearable Electrochemical Sensor Based on a Molecularly Imprinted Polymer Integrated with a Copper Benzene-1,3,5-Tricarboxylate Metal-Organic Framework for the On-Body Monitoring of Cortisol in Sweat

Tang,

2024

Polymers

View full text Add to dashboard Cite

Owing to their potential to transform traditional medical diagnostics and health monitoring, wearable biosensors have become an alternative evolutionary technology in the field of medical care. However, it is still necessary to overcome some key technique challenges, such as the selectivity, sensitivity, and stability of biometric identification. Herein, a novel, wearable electrochemical sensor based on a molecularly imprinted polymer (MIP) integrated with a copper benzene-1,3,5-tricarboxylate metal–organic framework (MOF) was designed for the detection of stress through the on-body monitoring of cortisol in sweat. The MOF was used as the substrate for MIP deposition to enhance the stability and sensitivity of the sensor. The sensor consisted of two layers, with a microfluidic layer as the top layer for spontaneous sweating and a modified electrode as the bottom layer for sensing. The sensor measured cortisol levels by detecting the current change that occurred when the target molecules bound to the imprinted cavities, using Prussian blue nanoparticles embedded in the MIP framework as the REDOX probe. The proposed sensor exhibited a linear detection range of 0.01–1000 nM with a detection limit of 0.0027 nM, and favorable specificity over other analogies. This facile anti-body free sensor showed excellent stability, and can be successfully applied for in situ cortisol monitoring.

show abstract

A Wearable Electrochemical Sensor Based on a Molecularly Imprinted Polymer Integrated with a Copper Benzene-1,3,5-Tricarboxylate Metal-Organic Framework for the On-Body Monitoring of Cortisol in Sweat

Tang,

2024

Polymers

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

A low-fouling electrochemical biosensor based on BSA hydrogel doped with carbon black for the detection of cortisol in human serum

Cited by 1 publication

References 35 publications

A Wearable Electrochemical Sensor Based on a Molecularly Imprinted Polymer Integrated with a Copper Benzene-1,3,5-Tricarboxylate Metal-Organic Framework for the On-Body Monitoring of Cortisol in Sweat

A Wearable Electrochemical Sensor Based on a Molecularly Imprinted Polymer Integrated with a Copper Benzene-1,3,5-Tricarboxylate Metal-Organic Framework for the On-Body Monitoring of Cortisol in Sweat

Contact Info

Product

Resources

About