2024
DOI: 10.1002/pca.3468
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A Machine Learning‐Based Approach for the Prediction of Anticoagulant Activity of Hypericum perforatum L. and Evaluation of Compound Activity

Zhiyong Zhang,
Wennan Nie,
Yijing Zhang
et al.

Abstract: IntroductionHypericum perforatum L. (HPL) is extensively researched domestically and internationally as a medicinal plant. However, no reports of studies related to the anticoagulant activity of HPL have been retrieved. The specific bioactive components are unknown.ObjectiveThe aim of this study was to develop a machine learning (ML) method for rapid prediction of anticoagulant activity in HPL and evaluation of compound activity. Materials and methods.First, an in vitro anticoagulant activity assay was develop… Show more

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