A malignant differential diagnosis for Peyronie’s disease

A new method of measuring the stiffness of corpus cavernosum penis with ShearWave™ Elastography

“…16,17 The results of the analysis showed that the stiffness of CCP was linearly correlated with age and sex hormone levels. That was to say, the SWS of CCP would decrease linearly with increase in age, decrease in testosterone and increase in oestradiol.…”

A Case of Penile Metastasis from Prostate Cancer, Identified by 68Ga-PSMA PET/CT, Mimicking Peyronie’s Disease: A Diagnostic Challenge

“…Clinical presentation in this patient group frequently includes painless nodules in the corpus cavernosum or glans, penile skin changes, abnormal penile erection and priapism, urinary retention, pelvic, perineal, and penile pain, dyspareunia, and haematuria [7]. Therefore, penile metastases must be carefully considered as an important differential diagnosis of Peyronie's disease; however, misdiagnosis or misinterpretation of penile metastases as Peyronie's disease has occurred [8][9][10][11][12]. Most reported cases involve metastases from cancers other than prostate cancer [9][10][11][12].…”

“…Therefore, penile metastases must be carefully considered as an important differential diagnosis of Peyronie's disease; however, misdiagnosis or misinterpretation of penile metastases as Peyronie's disease has occurred [8][9][10][11][12]. Most reported cases involve metastases from cancers other than prostate cancer [9][10][11][12]. An instance of reported penile metastases originating from prostate cancer, initially misdiagnosed as Peyronie's disease, was observed during the primary staging of the disease and distinguished by a significant dissemination of malignancy [8].…”