A masquerading subcutaneous swelling caused by Scedosporium apiospermum: An emerging pathogen

Abstract

Scedosporiasis is an emerging infection in immunocompromised individuals. We report a case of multiple subcutaneous swellings in a diabetic ketoacidotic patient, which was clinically diagnosed as lipoma. On fine-needle aspiration cytology, pus was aspirated, which showed septate branching hyphal elements. The pus culture on Sabouraud's dextrose agar yielded Scedosporium apiospermum, which was identified based on its macroscopic and microscopic features. There are very few reports of scedosporiasis from India. The diagnosis of scedosporiasis is difficult and correct etiological diagnosis can help in better management of the patient.

Histopathological clues in the diagnosis of fungal infection by Scedosporium in a case of endophthalmitis starting as conjunctivitis

“…Reports showing morphological images of the fungus in histopathological slides are not so frequent; some of them are indeed cases of endophthalmitis . However, few if any of such reports emphasize and describe the morphological peculiarities of the Scedosporium in tissue or the morphological clues in the differential diagnosis with other fungi …”

“…6 However, few if any of such reports emphasize and describe the morphological peculiarities of the Scedosporium in tissue or the morphological clues in the differential diagnosis with other fungi. 7 In the current article, we focus on some of the most distinctive morphological features of Scedosporium infection in a biopsy. We particularly note the features that are not shared by Aspergillus or Fusarium spp., and which are therefore most important for the differential diagnosis.…”