of substances to the environment and thus can produce misleading results. Therefore, emission based indicators are more accurate in representing actual impacts.Today, detailed process design tasks involve simulation, evaluation and optimization of the entire process. In fact, optimization is one of the most important steps in any chemical process design. Over the past decade, optimization of environmental performance has started to incorporate alongside traditional economic criteria. Several systematic methodologies are available for detailed characterization of environmental impacts of chemicals, products and processes and have been incorporated into the design and optimization of chemical processes. The most commonly used methods are Life Cycle Assessment (LCA) (Azapagic and Clift, 1999a, b;Azapagic, 1999), Methodology of Environment Impact Minimization (MEIM) (Stefanis and Pistikopoulos, 1997), Waste ReductionIncreasing social pressure and strict legislations have resulted in changing the approach of traditional design practices to incorporate multiple objectives in the design of process plants. Distillation is one of the major operations in the chemical process industry that is widely used for purifying products or recovering solvents or separation of valuable reactants from waste stream. In this paper, a procedure for multi-objective optimization is discussed with the help of a distillation unit from hydrocarbon recovery plant of a distillate fraction process. The procedure developed here consists of four stages and is based on current design tools. The aim is to support decisions during design phase and optimize the process variables in order to generate a process with improved economics along with satisfaction of environmental objectives. Total potential environment impact and total annualized cost are used as indicator for environmental and economic objectives, respectively. La pression sociale croissante et les législations strictes ont eu pour effet de modifi er la manière traditionnelle de concevoir les pratiques de façon à inclure des objectifs multiples dans la conception des installations de procédés. La distillation est une des opérations importantes de l'industrie des procédés chimiques et est largement utilisée pour purifi er des produits ou récupérer des solvants, ou encore pour séparer les réactifs intéressants dans les courants de résidus. On analyse dans cet article une méthode d'optimisation à objectifs multiples à l'aide d'une unité de distillation venant d'une installation de récupération d'hydrocarbures d'un procédé de fraction de distillat. La méthode mise au point ici consiste en quatre phases et utilise des outils de conception courants. Le but est d'appuyer les décisions lors de la phase de la conception et d'optimiser les variables de procédés afi n de fournir un procédé offrant de meilleures économies ainsi que la satisfaction de répondre à des objectifs environnementaux. L'impact environnemental potentiel total et le coût annualisé total sont utilisés comme indicateurs pour les obj...