A medical costs study of older patients with acute myocardial infarction and metabolic syndrome in&amp;nbsp;hospital

Fan, Guo-Chang; Fu, Kang; Jin, Cheng-wei; Wang, Xiaozhen; Han, Lu; Wang, Hui; Zhong, Ming; Zhang, Yun; Zhang, Wei; Wang, Zhi-Hao

doi:10.2147/cia.s70372

Cited by 8 publications

(4 citation statements)

References 23 publications

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“…In our study, the length of stay was not significantly different between the two age groups, although other studies have shown that older patients with ACS had longer hospital stays. 30 , 31 Besides, in-hospital mortality was 7.4% among older patients and 0.9% among younger patients. Patients who were discharged from the hospital were followed by general cardiologists in an outpatient setting after an average of one month and then every year.…”

Section: Discussionmentioning

confidence: 95%

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Differences in Clinical Nature and Outcome Among Young Patients Suffering from an Acute Coronary Syndrome

Al-Shahrani¹,

Katbi²,

Al-Sharydah³

et al. 2021

JBM

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Purpose: Acute coronary syndrome (ACS) is a life-threatening cardiac disease identified by acute, regional reductions in coronary blood flow, resulting in myocardial ischemia, or infarction, and manifesting as discomfort in the chest area, neck, or arms. Frequently, ACS is provoked by an atherosclerotic plaque; therefore, coronary atherosclerosis is converted into a chronic disease to an acute medical emergency. The purpose of this study was to explore the differences among these variables in patients less than 45 years of age suffering from this major health problem compared to older adults admitted with an ACS diagnosis, and to adopt an optimized temporary management. Patients and Methods: A retrospective chart review study was conducted on a total of 652 ACS patients admitted at King Fahad Hospital of the University (KFHU) between 2015 and 2020. The patients' medical records were utilized for obtaining demographic data, presenting symptoms, risk factors, and clinical outcomes. Results: Overall, 652 patients were enrolled. Of these, 109 patients (16.7%) were under 45, with a mean age of 38 ± 7. Younger patients showed a higher rate of palpitation (23.9% versus. 13.6%; P = 0.019). A positive smoking history and a family history of CAD were seen more often in younger patients (42.2% vs 27.3%, P < 0.001; 22.9% vs 9.4%, P < 0.001, respectively). Older patients had greater renal impairment with higher creatinine (median = 1.10 mg/dl (range, 0.3-13.0) vs 1.0 (0.3-19.0; p = 0. 001), BUN (median = 16.0 (mange, 0.9-141.0) vs 12.0 (0.9-49.0); P < 0.001)). Younger patients had higher levels of LDL and total cholesterol (median 138c. 115; p < 0.001) and cholesterol (median 209 vs 178.5; p < 0.001). Hospital mortality was 0.9% in younger patients versus 7.4% in older patients (P = 0.004). Conclusion: Palpitations, smoking, family history, higher LDL levels, and total cholesterol levels were more prevalent in adults younger than 45 years old with ACS. Impaired renal function, hypertension, and diabetes were more in older patients with ACS.

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Section: Discussionmentioning

confidence: 95%

Section: Dovepressmentioning

confidence: 99%

Differences in Clinical Nature and Outcome Among Young Patients Suffering from an Acute Coronary Syndrome

Al-Shahrani¹,

Katbi²,

Al-Sharydah³

et al. 2021

JBM

View full text Add to dashboard Cite

show abstract

“…Similarly, in a study conducted in Italy, which followed up patients for 12 months’ post-hospitalization for ACS, patients who died of a cardiovascular event had an average cost of around €16,000 compared with an average cost of around €11,000 for the entire ACS cohort [ 8 ]. In China, a small study in a single hospital in Shandong found that increased age was associated with increased treatment costs and poorer clinical outcomes [ 9 ]. In a study in the US of over 12,000 patients with ACS, which compared those with and without diabetes, the presence of diabetes was reported to incur significant additional hospitalization costs of $32,577 versus no diabetes $29,150 [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Predictors of high-cost hospitalization in the treatment of acute coronary syndrome in Asia: findings from EPICOR Asia

Jan

Lee

Sawhney

et al. 2018

BMC Cardiovasc Disord

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BackgroundThe EPICOR Asia (long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients in Asia) study (NCT01361386) was an observational study of patients hospitalized for acute coronary syndromes (ACS) enrolled in 218 hospitals in eight countries/regions in Asia. This study examined costs, length of stay and the predictors of high costs during an ACS hospitalization.Methods and resultsData for patients hospitalized for an ACS (n = 12,922) were collected on demographics, medical history, event characteristics, socioeconomic and insurance status at discharge. Patients were followed up at 6 weeks’ post-hospitalization for an ACS event to assess associated treatment costs from a health sector perspective. Primary outcome was the incurring of costs in the highest quintile by country and index event diagnosis, and identification of associated predictors. Cost data were available for 10,819 patients. Mean length of stay was 10.1 days. The highest-cost countries were China, Singapore, and South Korea. Significant predictors of high-cost care were age, male sex, income, country, prior disease history, hospitalization in 3 months before index event, no dependency before index event, having an invasive procedure, hospital type and length of stay.ConclusionsSubstantial variability exists in healthcare costs for hospitalized ACS patients across Asia. Of concern is the observation that the highest costs were reported in China, given the rapidly increasing numbers of procedures in recent years.Trial registration NCT01361386 . Electronic supplementary materialThe online version of this article (10.1186/s12872-018-0859-4) contains supplementary material, which is available to authorized users.

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“… 12 . On the other hand, Fan and colleagues and Kanitz and colleagues have shown in their studies longer hospital stays in older patients with ACS 25 , 26 .…”

Section: Discussionmentioning

confidence: 91%

Acute coronary syndrome in young (≤45 Years) patients: a multicenter observational study

Shrateh,

Al-Tawil,

Awad

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction: Acute Coronary Syndrome (ACS) in young individuals (≤45 y) is increasingly recognized as a significant health concern, yet research in this demographic remains limited, particularly within the Palestinian context. This study aims to bridge this gap by comprehensively investigating the clinical characteristics, age-specific profiles, gender disparities, treatment modalities, and angiographic patterns of ACS in young patients compared to their older counterparts. Materials and Methods: A multicenter observational study was conducted, enrolling 468 participants aged 18-55 diagnosed with ACS and admitted to three prominent Palestinian hospitals. Data were collected from medical records, and statistical analysis was performed to assess demographic characteristics, clinical presentations, risk factors, treatment strategies, and outcomes. Results: The majority of participants were male (87%), with a higher proportion in the older age group (>45 y). Clinical presentations varied, with Non-ST Segment Elevation Myocardial Infarction (NSTEMI) being the most common diagnosis (48%). Risk factors such as smoking, hypertension, and diabetes were prevalent, with notable gender and age-specific differences. Percutaneous Coronary Intervention (PCI) was the predominant treatment strategy (83%), with consistent medication use across age groups. Conclusion: ACS in young patients poses a significant public health challenge in Palestine, necessitating tailored preventive strategies and comprehensive management approaches. Understanding the unique demographic and clinical characteristics of young ACS patients is crucial for informing targeted interventions and policies aimed at reducing the burden of cardiovascular disease in this population. These findings contribute valuable insights to the existing literature and underscore the importance of further research in this area to improve outcomes and mitigate the impact of ACS in young individuals globally.

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A medical costs study of older patients with acute myocardial infarction and metabolic syndrome in hospital

Cited by 8 publications

References 23 publications

Differences in Clinical Nature and Outcome Among Young Patients Suffering from an Acute Coronary Syndrome

Differences in Clinical Nature and Outcome Among Young Patients Suffering from an Acute Coronary Syndrome

Predictors of high-cost hospitalization in the treatment of acute coronary syndrome in Asia: findings from EPICOR Asia

Acute coronary syndrome in young (≤45 Years) patients: a multicenter observational study

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