A medication self-management program to improve adherence to HIV therapy regimens

Smith, Scott; Rublein, John; Marcus, Cheryl; Brock, Tina Penick; Chesney, Margaret A.

doi:10.1016/s0738-3991(02)00127-1

Cited by 105 publications

(106 citation statements)

References 27 publications

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“…25,44,45 Randomised controlled trials in Europe and the United States have confirmed that dedicating time to individualised counselling and education increases patients' sense of self-worth and efficacy. [46][47][48] Although this may not be feasible in Africa given the current capacity challenges, patients should nevertheless be systematically screened for depressive diseases and treated accordingly.…”

Section: Discussionmentioning

confidence: 99%

Adherence to antiretroviral therapy, virologic failure and workload at the Rustenburg Provincial Hospital

Chabikuli

Datonye

Nachega

et al. 2010

South African Family Practice

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SA Fam Pract 2010;52(4):350-355Background: Adherence to antiretroviral therapy (ART) is a strong predictor of progression to AIDS and death. It remains the most important potentially alterable factor that determines treatment outcomes. Methods:The study is a cross-sectional survey of self-reported adherence to ART and associated factors. The clinic had a tenfold increase in patient enrolment and a ninefold decline in staff-to-patient ratio, and the proportion of patients lost to follow-up doubled in the preceding four years.Conclusion: Adherence to ART was poor. The capacity of the clinic to manage patients adequately has declined significantly. Decentralisation of ART services to primary health care facilities should be considered.Peer reviewed.

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Section: Discussionmentioning

confidence: 99%

Adherence to antiretroviral therapy, virologic failure and workload at the Rustenburg Provincial Hospital

Chabikuli

Datonye

Nachega

et al. 2010

South African Family Practice

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“…We used the Hopkins Symptom Checklist to measure depression, the Berger Stigma Instrument, the Duke University of North Carolina Social Support Scale, and the Medical Outcomes Study HIV Quality of Life questionnaires [20][21][22][23]. For self-efficacy, we used a scale derived by our sister organization, Prevention and Access to Care and Treatment (PACT), which was adapted from the HIV Self-Efficacy Questionnaire [24], as well as the Confidence in Diabetes Self-Care Scale [25] and HIV self-management items specific to medication adherence developed and tested by Smith and colleagues [26]. With the exception of the Berger Stigma Instrument and HIV Self-efficacy Questionnaire, all instruments had been previously validated in Spanish.…”

Section: Data Collection and Measuresmentioning

confidence: 99%

Matching Social Support to Individual Needs: A Community-Based Intervention to Improve HIV Treatment Adherence in a Resource-Poor Setting

et al. 2010

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From December 2005 to April 2007, we enrolled 60 adults starting antiretroviral therapy (ART) in Lima, Peru to receive community-based accompaniment with supervised antiretrovirals (CASA), consisting of 12 months of DOT-HAART, as well as microfinance assistance and/or psychosocial support group according to individuals' need. We matched 60 controls from a neighboring district, and assessed final clinical and psychosocial outcomes at 24 months. CASA support was associated with higher rates of virologic suppression and lower mortality. A comprehensive, tailored adherence intervention in the form of community-based DOT-HAART and matched economic and psychosocial support is both feasible and effective for certain individuals in resource-poor settings.

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“…We used the Hopkins Symptom Checklist to measure depression, the Berger Stigma Instrument, the Duke University of North Carolina Social Support Scale, and the Medical Outcomes Study HIV Quality of Life questionnaires (Berger et al 2001;Broadhead et al 1988;Derogatis et al 1974;Wu et al 1991). For self-efficacy, we used a scale derived by our sister organization, PACT, which was adapted from the HIV Self-Efficacy questionnaire (Shively et al 2002), as well as the Confidence in Diabetes Self-Care Scale (Van Der Ven et al 2003) and HIV self-management items specific to medication adherence developed and tested by Smith et al (2003). The validation and internal reliability of these instruments in our cohort has been described elsewhere (Shin et al 2008).…”

Section: Data Collection and Measuresmentioning

confidence: 99%

Community-based DOT-HAART Accompaniment in an Urban Resource-Poor Setting

et al. 2009

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From December 2005 to April 2007, we enrolled 60 adults starting antiretroviral therapy (ART) in a health district of Lima, Peru to receive community-based accompaniment with supervised antiretroviral (CASA). Paid community health workers performed twice-daily home visits to directly observe ART and offered additional medical, social and economic support to CASA participants. We matched 60 controls from a neighboring district by age, CD4 and primary referral criteria (TB status, female, neither). Using validated instruments at baseline and 12 months (time of DOT-HAART completion) we measured depression, social support, quality of life, HIV-related stigma and self-efficacy. We compared 12 month clinical and psychosocial outcomes among CASA versus control groups. CASA participants experienced better clinical and psychosocial outcomes at 12 months, including proportion with virologic suppression, increase in social support and reduction in HIV-associated stigma.

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A medication self-management program to improve adherence to HIV therapy regimens

Cited by 105 publications

References 27 publications

Adherence to antiretroviral therapy, virologic failure and workload at the Rustenburg Provincial Hospital

Adherence to antiretroviral therapy, virologic failure and workload at the Rustenburg Provincial Hospital

Matching Social Support to Individual Needs: A Community-Based Intervention to Improve HIV Treatment Adherence in a Resource-Poor Setting

Community-based DOT-HAART Accompaniment in an Urban Resource-Poor Setting

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