In order to promote the research process of information security in the whole society, improve the safety factor of computer data communication, strengthen computer security management, the author proposes a computer data encryption strategy that combines the strong security of the 3DES encryption algorithm and the asymmetric encryption advantages of the RSA algorithm. Through the detailed analysis of DES encryption algorithm and 3DES encryption, creatively uses the RSA encryption algorithm to improve the single 3DES algorithm, consolidates the performance of the 3DES encryption algorithm to ensure data communication, and ensures the data integrity, better improve encryption performance. Experiments show that: The proposed encryption algorithm improves security performance by 10 times, and the response efficiency is only 1 ms away from other algorithms, compared with other algorithms, it has better encryption performance and is suitable for actual computer data communication scenarios. Conclusion: The encryption algorithm proposed by the author has achieved good results in terms of security performance and response efficiency, it is suitable for actual computer data security communication and can effectively improve computer security management.