A Meta-Analysis – Aerobic and Resistance Exercises Intervention Affect on Blood Glucose Level among Type 2 Diabetes Patients

Abstract

Context: Exercise is an effective strategy and support to have favorable for glucose control in type 2 diabetes patients. Furthermore, aerobic and resistance exercises examined aerobic, resistance, and combine form exercise blood glucose control among type 2 diabetes patients although, gender of male and female had divergence age range from 20 to 88 years description and cointervention of diet added additional support to result. Objective: The meta-analysis examined that above 8 weeks exercises intervention (aerobic, resistance, and combine form exercise) and its impact on hemoglobin A1c (Hba1c) and fasting blood glucose (FBG) control among type 2 diabetes patients. Data Sources: In the Web of Science searched full texted journal papers were taken about 179 and Pub Med database provided 58 full text journal papers, and its above 1990 years research papers search term used by phrases, truncation, and Boolean operator. Study Selection: The selected studies that evaluated the varied exercise regimen impact >8 weeks duration in type 2 diabetes patients. Twenty-four randomized controlled studies included total participants sample size of 1578 post-intervention exercise and control group. Included studies cointervention of drugs excluded. Data Extraction: Two reviewers extract the data baseline and post-intervention, then mean and standard deviation for exercise and control groups. Included study characteristics table, practice of exercise protocols and evaluate the methodological quality and potential bias. Results: Overall Hba1c variable data were taken on type 2 diabetes patients totally 1505 participants included in 22 studies post-values on exercises and control groups overall effect size reduced Hba1c favors exercise group would significant difference value P = 0.00001 and standardized mean difference SMD= −0.40% (−11.5 mg/dl), 95% Confidence interval (CI) (−0.54, −0.27) random effect model, heterogeneity observed (I2=23%) no significant value P = 0.16. Effect size reduced FBG which would exercise favors significant difference value P = 0.0001 and SMD= −0.41% (−11.8 mg/dl), 95% CI (−0.59, −0.24) random effect model, heterogeneity observed (I2=53%) significant value P = 0.002. Conclusion: This meta-analysis evidence supported varied exercise regimen and its impact on Hba1c and FBG level concern designed that overall significant impact on intervention such as aerobic, resistance, and combine form exercise (aerobic and resistance exercise) among type 2 diabetes patients. Although, combined exercise had highly better effective strategy results than aerobic or resistance alone, duration >8 weeks, exercise frequency 3 or 5 days/week and combined exercise followed aerobic consecutively and then resistance exercises.