A meta-analysis of contagious caprine pleuropneumonia (CCPP) in Ethiopia

Asmare, Kassahun; Abayneh, Takele; Mekuria, Solomon; Ayelet, Gelagay; Sibhat, Berhanu; Skjerve, Eystein; Szonyi, Barbara; Wieland, Barbara

doi:10.1016/j.actatropica.2016.02.023

Cited by 22 publications

(24 citation statements)

References 22 publications

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“…For unvaccinated population of goats this figure is high and requires attention of the veterinary and livestock authority of the area to minimize the effect CCPP has on livelihoods in the community. The overall prevalence of CCPP in the present study was higher than the national prevalence estimated from pooled sero-prevalence (25.7%) through a systematic review by Asmare et al (2016) and is largely in agreement with the previous findings from Ethiopia (Lakew et al 2014) in which 31.6% of goats in Borana were found to be positive to CCPP. Similar observations were also made earlier in goats at an export abattoir at Bishoftu, Ethiopia (Eshetu et al 2007), and Southern Ethiopia, in Tigray and Afar (Hadush et al 2009), and in Beetal goats in Pakistan (Sherif et al 2012; Hussain et al 2012).…”

Section: Discussionsupporting

confidence: 92%

“…Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subspecies capripneumoniae ( Mccp ) is a severe and devastating respiratory disease with high morbidity and mortality in goats (Sadique et al 2012; Tsehay et al 2014), causing considerable economic losses (Asmare et al 2016). It occurs in many countries in Africa, Asia, and Middle East (Prats-van der Ham et al 2015) and is a classical trans-boundary animal disease (Shahzad et al 2016).…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, the disease is included in the list of notifiable diseases of the World Organization for Animal Health (OIE 2008) as it threatens a significant number of goat populations throughout the world and has a considerable socioeconomic impact in infected territories (Atim et al 2016). Though disease is mainly found in goats, subclinical cases were reported in sheep and some wild ruminant species (Asmare et al 2016).…”

Section: Introductionmentioning

confidence: 99%

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Epidemiological investigations of contagious caprine pleuropneumonia in selected districts of Borana zone, Southern Oromia, Ethiopia

Teshome¹,

Sori

Sacchini

et al. 2018

Trop Anim Health Prod

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From November 2016 to April 2017, a cross-sectional study to determine the sero-prevalence of contagious caprine pleuropneumonia (CCPP) and to investigate its epidemiology was conducted in selected districts of Borana zone in Ethiopia. In addition, the study aimed at identifying Mccp antigens using species specific primer of PCR. A multistage random sampling was implemented to select districts, pastoral associations (villages), and households. A total of 890 serum samples of small ruminants that had not been vaccinated (goats n = 789 and sheep n = 101) were collected and screened for the presence of antibodies against Mycoplasma capricolum subspecies capripneumoniae using a competitive enzyme-linked immunosorbent assay. Lung tissues and pleural fluid samples were collected from 3 sero-positive and clinically suspected goats for isolation of Mycoplasma capricolum subspecies capripneumoniae . Serology showed that overall 31.2% (246/789) of goats and 12.9% (13/101) of sheep were positive with statistically significant differences between districts ( p = 0.001). Multivariable logistic regression analysis revealed that goats from Moyale and Yabello districts had higher odds of being positive than goats from Elwoya district with odd ratios of 2.05 and 1.61, respectively. Age of goats was also significantly associated with sero-positivity (OR = 1.47; CI 95% 1.2–1.8). Mycoplasma capricolum subspecies capripneumoniae was identified in 6 (75%) of the tissue samples using species-specific primer of PCR. Besides improving the understanding of the epidemiology of CCPP in the selected districts and demonstrating its wide distribution, the study highly also provides evidence of the possible role of sheep in the maintenance of the disease.

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Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Epidemiological investigations of contagious caprine pleuropneumonia in selected districts of Borana zone, Southern Oromia, Ethiopia

Teshome¹,

Sori

Sacchini

et al. 2018

Trop Anim Health Prod

Self Cite

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“…The study relies on the hypothesis that this case definition leads to an overall underestimation of the CCPP‐related mortality cases due to a higher frequency of non‐diagnosed cases compare to the cases misdiagnosed as CCPP. This seems realistic taking into account that the CCPP and its necropsy signs are well known by the pastoralists in endemic areas (Asmare et al, ).…”

Section: Methodsmentioning

confidence: 99%

“…Several studies report CCPP as one of the main infectious diseases affecting the goats in the ASALs (Bett, Jost, Allport, & Mariner, ; Kipronoh et al, ; Peyraud et al, ). The disease is well known by the pastoralists who describe it as a respiratory disease with a high mortality rate identifiable by its pathognomonic necropsy lesions of fibrinous pleuropneumonia (Asmare et al, ). These lesions are described by the pastoralists as ‘adhesions between lungs and ribs’.…”

Section: Introductionmentioning

confidence: 99%

Economic impact of contagious caprine pleuropneumonia and cost–benefit analysis of the vaccination programmes based on a one‐year continuous monitoring of flocks in the arid and semi‐arid lands of Kenya

Renault

Hambe

Vlaenderen³

et al. 2019

Transbound Emerg Dis

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In Kenya and East Africa, contagious caprine pleuropneumonia (CCPP) is one of the most prevalent infectious diseases affecting small ruminants in pastoral areas with adverse consequences on livelihoods. This is so despite the implementation of bi‐annual vaccination campaigns. Unfortunately, the impact of the disease and the cost‐effectiveness of its prevention and control in a pastoral context have been difficult to assess due to a lack of reliable data. The dynamic of flock population, high illiteracy and limited outreach are the main challenges for proper data collection. Nevertheless, such analysis is important to justify the implementation of national vaccination campaign for livestock disease control and to contribute to pastoral households’ economy support programme. A continuous flock monitoring was performed for a year in Turkana County to collect data on flock dynamics and the different causes of mortalities. A stochastic model was developed to evaluate the annual economic losses due to CCPP in a standard flock of 100 heads and evaluate the cost–benefit ratio of the vaccination programmes based on different scenarios of 95%, 50% and 20% vaccination effectiveness. The annual economic losses due to CCPP for a standard flock of 100 heads were estimated at Euros 1,712.66 in average. The benefits‐costs ratio of the vaccination supports the current bi‐annual vaccination campaigns, even with a vaccine effectiveness limited to 20% (average benefits‐costs ratio of 5.715 with SD of 3.914). This justifies the campaigns as part of a food security or livelihood support programme. However, from an overall health perspective and for long‐term effects on livestock asset protection and disease control, a higher vaccination effectiveness is required.

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Contagious Caprine Pleuropneumonia

Manso-Silván¹,

Thiaucourt²

2019

Transboundary Animal Diseases in Sahelian Africa and Connected Regions

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A meta-analysis of contagious caprine pleuropneumonia (CCPP) in Ethiopia

Cited by 22 publications

References 22 publications

Epidemiological investigations of contagious caprine pleuropneumonia in selected districts of Borana zone, Southern Oromia, Ethiopia

Epidemiological investigations of contagious caprine pleuropneumonia in selected districts of Borana zone, Southern Oromia, Ethiopia

Economic impact of contagious caprine pleuropneumonia and cost–benefit analysis of the vaccination programmes based on a one‐year continuous monitoring of flocks in the arid and semi‐arid lands of Kenya

Contagious Caprine Pleuropneumonia

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